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Search for syphilis treatment in all Journal Watch editions
Physician-authored summaries on the latest research on syphilis treatment, editorials on syphilis treatment, and perspectives on syphilis treatment - drawn from the top medical journals.
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Syphilis Treatment in a Resource-Poor Setting
- February 11, 2005
- Linda M. Mundy, MD
- Infectious Diseases
Use of multidose parenteral therapy increases the difficulty of treating sexually transmitted diseases (STDs), particularly in resource-poor settings. Researchers recently evaluated the outcomes of syphilis . . .- Reviewing:
- Kiddugavu MG et al., Sex Transm Dis 2005 Jan; 32:1-6.
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Standard Syphilis Treatment May Suffice in HIV Infection
- September 1, 1997
- A Zuger
- Dermatology
When a patient with syphilis is also HIV-infected, standard syphilis treatment occasionally does not work; neurologic progression, serofast disease, and other aberrant responses have been . . .- Reviewing:
- Rolfs RT et al., N Engl J Med 1997 Jul 31; 337:
307 314 .
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STANDARD SYPHILIS TREATMENT MAY SUFFICE IN HIV INFECTION.
- August 15, 1997
- A Zuger
- General Medicine
When a patient with syphilis is also HIV-infected, standard syphilis treatment occasionally does not work: neurologic progression, serofast disease, and other aberrant responses have been . . .- Reviewing:
- Rolfs RT et al., N Engl J Med 1997 Jul 31; 337:
307 314 .
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Syphilis and HIV: The Intersection of Two Epidemics Free
- September 3, 2010
- Becky A. Miller, MD, and Charles B. Hicks, MD
- HIV/AIDS
A comprehensive review of the epidemiology, clinical presentation, diagnosis, treatment, and monitoring of syphilis in HIV-infected patients -
More on Diagnosing Neurosyphilis in HIV-Infected Patients
- February 23, 2009
- Abigail Zuger, MD
- HIV/AIDS
A new analysis suggests that the present CDC-recommended protocol may underestimate the prevalence of asymptomatic neurosyphilis.- Reviewing:
- Ghanem KG et al., Clin Infect Dis 2009 Mar 15; 48:816.
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A New Wrinkle in Syphilis Testing
- August 27, 2008
- Stephen G. Baum, MD
- Infectious Diseases
Reversal of the traditional syphilis screening test algorithm reveals cases that would have been missed before.- Reviewing:
- Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2008 Aug 15; 57:872.
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New Testing Combination May Reveal Latent Syphilis Free
- August 15, 2008
- Physician's First Watch
Reversing the usual order of syphilis tests produces additional positive results that may require treatment for late latent syphilis, according to a CDC study in... -
Syphilis and HIV Infection
- July 14, 2008
- Carlos del Rio, MD, and Jodie Dionne-Odom, MD
- HIV/AIDS
In a study of patients with HIV and syphilis, greater immunosuppression at syphilis diagnosis was associated with the development of neurosyphilis and with serologic failure after adequate syphilis treatment. Conversely, potent ART reduced the likelihood of both outcomes.- Reviewing:
- Ghanem KG et al., AIDS 2008 Jun 19; 22:1145. Ghanem KG et al., Clin Infect Dis 2008 Jul 15; 47:258.
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When Should You Look for Neurosyphilis?
- May 1, 2004
- Abigail Zuger, MD
- HIV/AIDS
Data from a large study of syphilis indicate a high rate of neurosyphilis in HIV-infected patients with a CD4-cell count less than or equal to 350 or a serum RPR titer greater than or equal to 1:32.- Reviewing:
- Marra CM et al., J Infect Dis 2004 Feb 1; 189:369-76.
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HIV and Syphilis Coinfection: Trends and Interactions
- February 1, 2003
- Sigall Kassutto, MD, and Paul E. Sax, MD
- HIV/AIDS
Recent reports indicate that syphilis incidence is rising in the U.S. This article reviews the current literature on the epidemiology of syphilis, as well as its clinical manifestations, diagnosis, and treatment in the setting of HIV infection. -
Beyond Penicillin for Syphilis?
- September 20, 2002
- Linda M. Mundy, MD
- Infectious Diseases
Early syphilis remains among the 10 most common reportable infectious diseases in the U.S. The accepted treatment for early syphilis is intramuscular benzathine penicillin G . . .- Reviewing:
- Hook EW III et al., Sex Transm Dis 2002 Aug; 29:486-90.
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Maternal Syphilis and Successful Treatment
Appropriate penicillin treatment of pregnant women diagnosed with syphilis usually prevents active congenital syphilis in newborns. However, prophylactic failures do occur, and affected infants need . . .- Reviewing:
- Sheffield JS et al., Am J Obstet Gynecol 2002 Mar; 186:569-73.
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Syphilis and HIV Disease: Symptoms, Signs, Serology, and Treatment Response
- April 1, 1993
- Johnson
- Dermatology
Many infections behave differently in persons with advanced HIV disease. Syphilis occurring with HIV disease may have an altered time course (meningovascular symptoms occurring within . . .- Reviewing:
- Gourevitch MN et al., Ann Intern Med 1993 Mar 1; 118:
350 355 .
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