- Home>
- Journal Watch
- >
- statin therapy
Search for statin therapy in all Journal Watch editions
Physician-authored summaries on the latest research on statin therapy, editorials on statin therapy, and perspectives on statin therapy - drawn from the top medical journals.
Sort by:
Items 1 to 20 of 216 results - Relevance
- Date
You searched for: statin therapy
-
Should Statin Therapy Be Continued During Sepsis?
- April 20, 2011
- Neil M. Ampel, MD
- Infectious Diseases
In a randomized, placebo-controlled trial, continuing statin therapy during hospitalization for sepsis neither improved nor worsened outcome.- Reviewing:
- Kruger PS et al., Am J Respir Crit Care Med 2011 Mar 15; 183:774.
-
Intensive Statin Therapy Prevents Nonfatal Cardiovascular Events
- August 30, 2006
- Harlan M. Krumholz, MD, SM
- Cardiology
Results are in from an industry-funded meta-analysis of four major randomized trials comparing intensive with moderate statin therapy.- Reviewing:
- Cannon CP et al., J Am Coll Cardiol 2006 Aug 1; 48:438-45.
-
Does Intensive Statin Therapy After ACS Prevent Incident Heart Failure?
- July 26, 2006
- Frederick A. Masoudi, MD, MSPH
- Cardiology
Yes, according to data from the PROVE IT-TIMI 22 trial.- Reviewing:
- Scirica BM et al. for the PROVE IT-TIMI 22 Investigators., J Am Coll Cardiol 2006 Jun 6; 47:2326-31.
-
High-Intensity Statin Therapy Leads to Regression of Coronary Atherosclerosis
- May 23, 2006
- John A. Marx, MD, FAAEM, FACEP
- Emergency Medicine
Changes occurred after 2 years of statin therapy.- Reviewing:
- Nissen SE et al., JAMA 2006 Apr 5; 295:1556-65. Blumenthal RS and Kapur NK., JAMA 2006 Apr 5; 295:1583-4.
-
CRP and Outcomes After Statin Therapy
- January 14, 2005
- Allan S. Brett, MD
- General Medicine
Lower CRP levels after statin therapy are associated with improved outcomes, but what do these findings mean for the future of statin therapy?- Reviewing:
- Ridker PM et al., N Engl J Med 2005 Jan 6; 352:20-8. Nissen SE et al. , N Engl J Med 2005 Jan 6; 352:29-38.
-
Statin Therapy Is Effective and Safe for Children with Hypercholesterolemia
- August 30, 2004
- F. Bruder Stapleton, MD
- Pediatrics and Adolescent Medicine
Medication and lifestyle modification can brighten the outlook for adult health in affected children.- Reviewing:
- Wiegman A et al., JAMA 2004 Jul 21; 292:331-7.
-
Genetic Variation in Response to Statin Therapy
- August 6, 2004
- JoAnne M. Foody, MD
- Cardiology
The cholesterol-lowering effect of statins can vary according to patients' genetic profiles.- Reviewing:
- Chasman DI et al., JAMA 2004 Jun 16; 291:2821-7. Haga SB and Burke W., JAMA 2004 Jun 16; 291:2869-71.
-
Should We Start Statin Therapy Right After an ACS Episode?
- August 6, 2004
- JoAnne M. Foody, MD
- Cardiology
In several clinical trials, including PROVE-IT (Journal Watch Cardiology Apr 16 2004), intensive statin therapy has been associated with improved outcomes in acute . . .- Reviewing:
- Spencer FA et al. for the GRACE Investigators., Ann Intern Med 2004 Jun 1; 140:857-66. Laupacis A and Mamdani M., Ann Intern Med 2004 Jun 1; 140:923-4.
-
Statin Therapy in Children
- July 30, 2004
- Howard Bauchner, MD
- General Medicine
Both the obesity epidemic and accumulating evidence that cardiovascular disease has its origin in childhood have led to renewed interest in the efficacy and safety . . .- Reviewing:
- Wiegman A et al., JAMA 2004 Jul 21; 292:331-7.
-
Should We Use CRP to Target Patients for Statin Therapy?
- August 31, 2001
- JM Gore
- Cardiology
Patients with elevated levels of the inflammatory marker C-reactive protein (CRP) are at higher risk for adverse coronary events than are patients whose CRP levels . . .- Reviewing:
- Ridker PM et al for the Air Force/Texas Coronary Atherosclerosis Prevention Study Investigators., N Engl J Med 2001 Jun 28; 344:
1959 1965 .
-
Can C-Reactive Protein Help Target Patients for Statin Therapy?
- July 10, 2001
- AS Brett
- General Medicine
Elevated blood levels of C-reactive protein (CRP) predict increased risk for coronary events; moreover, statin drugs reduce CRP (JW Online Jul 10 2001, accession . . .- Reviewing:
- Ridker PM et al., N Engl J Med 2001 Jun 28; 344:
1959 1965 .
-
Post-CABG Outcomes with Preoperative Statin Therapy
- February 2, 2001
- JM Gore
- Cardiology
Failure to modify risk before coronary artery bypass grafting (CABG) significantly reduces long-term graft patency. To study the effects of preoperative lipid lowering on short-term . . .- Reviewing:
- Dotani MI et al., Am J Cardiol 2000 Nov 15; 86:
1128 1130 .
-
Non-HDL Cholesterol Seems a Better Target Than LDL to Gauge Statin Therapy Free
- March 28, 2012
- Physician's First Watch
LDL cholesterol levels may not be the best target for statin therapy, according to a JAMA meta-analysis.Researchers examined patient data from eight randomized... -
No Evidence of Adverse Outcomes from Long-Term Statin Therapy
- December 20, 2011
- Bruce Soloway, MD
- General Medicine
Vascular benefits persist, without elevated risk for nonvascular morbidity or cancer.
CME Exam- Reviewing:
- Heart Protection Study Collaborative Group., Lancet 2011 Dec 10; 378:2013.
-
Long-Term Statin Therapy Does Not Lower Risk for Atrial Fibrillation
- April 7, 2011
- Paul S. Mueller, MD, MPH, FACP
- General Medicine
Several factors might explain discrepant results between short-term and long-term trials.
CME Exam- Reviewing:
- Rahimi K et al., BMJ 2011 Mar 16; 342:d1250.
-
Statin Therapy and Atherosclerosis Regression Free
- February 6, 2007
- Thomas L. Schwenk, MD
- General Medicine
Reductions in LDL and increases in HDL were both important in reversing atherosclerosis.- Reviewing:
- Nicholls SJ et al., JAMA 2007 Feb 7; 297:499-508.
-
Statin Therapy and Underlying Neuromuscular Disorders Free
- December 12, 2006
- Ronan J. Walsh, MB, BCh
- Neurology
Four case reports suggest that neuromuscular disorders can be unmasked by statin therapy.- Reviewing:
- Tsivgoulis G et al., Arch Intern Med 2006 Jul 24; 166:1519-24.
-
Another Outcomes Test of Intensive Statin Therapy After ACS
- October 29, 2004
- JoAnne M. Foody, MD
- Cardiology
Simvastatin, at an intensive target dose of 80 mg/day, showed only trends toward benefit over a more conservative strategy in high-risk acute coronary syndrome patients.- Reviewing:
- de Lemos JA et al. for the A to Z Investigators., JAMA 2004 Sep 15; 292:1307-16. Nissen SE., JAMA 2004 Sep 15; 292:1365-7.
-
Are Risk Levels Being Used to Guide Statin Therapy in Elders?
- June 25, 2004
- JoAnne M. Foody, MD
- Cardiology
Current guidelines recommend use of statin therapy according to patients' 10-year risk for future cardiovascular events. Is this recommendation being followed in elders? Researchers gathered . . .- Reviewing:
- Ko DT et al., JAMA 2004 Apr 21; 291:1864-70.
-
Intensive vs. Moderate Statin Therapy: Effect on Atherosclerosis Progression
- April 16, 2004
- JoAnne M. Foody, MD
- Cardiology
Statin therapy reduces morbidity and mortality associated with coronary artery disease (CAD), but what is the optimal intensity of therapy? There has been little scientific . . .- Reviewing:
- Nissen SE et al. for the REVERSAL Investigators., JAMA 2004 Mar 3; 291:1071-80. Sacks FM., JAMA 2004 Mar 3; 291:1132-4.
Sort by:
Items 1 to 20 of 216 results - Relevance
- Date
