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Search for nicotine in all Journal Watch editions
Physician-authored summaries on the latest research on nicotine, editorials on nicotine, and perspectives on nicotine - drawn from the top medical journals.
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Nicotine Reprograms Reward Responses
- April 8, 2013
- Steven Dubovsky, MD
- Psychiatry
Some answers to the question of why it is so hard to quit smoking.- Reviewing:
- Rose EJ et al., Biol Psychiatry 2013 Feb 1; 73:280. Addy NA and Picciotto MR., Biol Psychiatry 2013 Feb 1; 73:205.
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A Single Shot for Nicotine Addiction
- July 23, 2012
- Barbara Geller, MD
- Psychiatry
In animals, a vaccine using an adeno-associated viral vector that expresses high levels of an antinicotine antibody shows persistent effects.- Reviewing:
- Hicks MJ et al., Sci Transl Med 2012 Jun 27;:
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Nicotine for MCI?
- February 7, 2012
- David S. Knopman, MD
- Neurology
A small study of a nicotine patch in patients with mild cognitive impairment showed some benefit on a reaction-time test but no effect according to clinicians' judgment.- Reviewing:
- Newhouse P et al., Neurology 2012 Jan 10; 78:91.
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Nicotine-Replacement Labels Can Change to Downplay Dual-Use Dangers Free
- April 2, 2013
- Physician's First Watch
The FDA is allowing makers of nicotine-replacement products to change their labeling "to allow some flexibility on how they are used and for how... -
Study Confirms Rise in Nicotine Delivery of Cigarettes Free
- January 19, 2007
- Physician's First Watch
A reanalysis of data released last summer confirms that the nicotine yield from cigarettes increased about 11% from 1998 to 2005. A Harvard School of... -
An Antinicotine Vaccine?
- March 11, 2013
- Joel Yager, MD
- Psychiatry
A proof-of-concept study suggests significant reductions in smoking, desire, and brain nicotine levels after vaccination.- Reviewing:
- Esterlis I et al., Am J Psychiatry 2013 Feb 22;:
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Electronic Cigarettes? A Shocking New Fad! Free
- November 10, 2010
- F. Bruder Stapleton, MD
- Pediatrics and Adolescent Medicine
Using e-cigarettes is widely marketed on the Internet as a safer alternative to smoking cigarettes, but are they safer? -
Smokers Are Hurting More Than Themselves
- September 27, 2010
- Steven Dubovsky, MD
- Psychiatry
Nicotine, whether through the placenta or secondhand smoke, is associated with psychiatric problems.- Reviewing:
- Ekblad M et al., Arch Gen Psychiatry 2010 Aug; 67:841. Hamer M et al., Arch Gen Psychiatry 2010 Aug; 67:850.
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Personalized Medicine for Quitting Smoking
- September 29, 2008
- Steven Dubovsky, MD
- Psychiatry
Another step toward personalized medicine- Reviewing:
- Patterson F et al., Clin Pharmacol Ther 2008 Sep; 84:320.
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Making Smoking Cessation Stick: Nicotine-Replacement Patches in Pregnancy Free
- February 29, 2012
- Allison Bryant, MD, MPH
- Women's Health
A randomized trial failed to show long-term benefit.- Reviewing:
- Coleman T et al., N Engl J Med 2012 Mar 1; 366:808. Oncken C., N Engl J Med 2012 Mar 1; 366:846.
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Hooked on Snus: Smokeless Tobacco and Nicotine Dependence
Users of smokeless tobacco reported similar or more symptoms of nicotine dependence as cigarette smokers.- Reviewing:
- Post A et al., Addiction 2010 Apr; 105:740.
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Extended Treatment with Transdermal Nicotine Is Effective
- February 16, 2010
- Richard Saitz, MD, MPH, FACP, FASAM
- General Medicine
Abstinence from smoking was more likely with longer use of the patch.- Reviewing:
- Schnoll RA et al., Ann Intern Med 2010 Feb 2; 152:144.
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Choose to Chew: Nicotine Gum and Pregnancy
- November 20, 2008
- Sandra Ann Carson, MD
- Women's Health
Women who chewed nicotine gum cut their daily smoking more than did women who chewed placebo gum.- Reviewing:
- Oncken C et al., Obstet Gynecol 2008 Oct; 112:859.
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Nicotine Replacement Therapy in the ICU
- June 12, 2007
- Allan S. Brett, MD
- General Medicine
Hospital mortality was higher among critically ill smokers who received nicotine replacement therapy.- Reviewing:
- Lee AH and Afessa B., Crit Care Med 2007 Jun; 35:1517-21.
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Quick Test for Salivary Nicotine Helps with Smoking Cessation
- December 2, 2005
- Keith I. Marton, MD
- General Medicine
Smokers might be more likely to quit if they have personalized information about the level of tobacco-related toxins in their bodies. However, laboratory testing for . . .- Reviewing:
- Barnfather KD et al., BMJ 2005 Oct 29; 331:999-1001.
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Free Nicotine Patches Led to Increased Smoking Cessation in NYC
- June 28, 2005
- Bruce Soloway, MD
- General Medicine
In recent years, New York City has raised cigarette taxes, banned smoking in most workplaces (including restaurants and bars), and promoted cessation through various other . . .- Reviewing:
- Miller N et al., Lancet 2005 May 28; 365:1849-54. Murphy M and Aveyard P., Lancet 2005 May 28; 365:1831-2.
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Nicotine Agonist Provides Modest Symptom Reduction for Adult ADHD Free
- October 22, 2012
- Peter Roy-Byrne, MD
- Psychiatry
In a proof-of-concept clinical trial, the highest dose of a novel nicotine agonist shows efficacy, but more effective medications are still needed.- Reviewing:
- Bain EE et al., Neuropsychopharmacology 2012 Oct 3;:
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Nicotine Patch No Better Than Placebo in Helping Pregnant Smokers Quit Free
- March 1, 2012
- Physician's First Watch
The nicotine patch is no better than placebo in helping pregnant smokers abstain from cigarettes until delivery, according to a New England Journal of Medicine... -
Nicotine Patches and Gum Found Ineffective Over the Long Term Free
- January 11, 2012
- Physician's First Watch
A study in the journal Tobacco Control casting doubt on the effectiveness of nicotine replacement therapy has garnered widespread media attention.Over several years, researchers... -
Extending Nicotine Patch Treatment Temporarily Increases Likelihood of Smoking Abstinence Free
- February 2, 2010
- Physician's First Watch
Using transdermal nicotine patches for 24 weeks rather than the standard 8 weeks increases smoking abstinence, but the effect lasts only as long as treatment...
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