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Search for manic depression in all Journal Watch editions
Physician-authored summaries on the latest research on manic depression, editorials on manic depression, and perspectives on manic depression - drawn from the top medical journals.
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You searched for: manic depression
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Antidepressants Don't Always Aggravate Bipolar Illness
- April 29, 2013
- Peter Roy-Byrne, MD
- Psychiatry
Bipolar II patients who respond acutely to fluoxetine alone may be maintained on this monotherapy.- Reviewing:
- Amsterdam JD et al., Br J Psychiatry 2013 Apr; 202:301. Thase ME., Br J Psychiatry 2013 Apr; 202:251.
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Functional Remediation for Bipolar Disorders
- April 8, 2013
- Joel Yager, MD
- Psychiatry
In a 21-week, multisite study, add-on functional remediation improved psychosocial functioning more than treatment as usual but not more than psychoeducation.- Reviewing:
- Torrent C et al., Am J Psychiatry 2013 Mar 20;:
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Perinatal Mood Episodes Common in Women with Bipolar Disorder
- March 18, 2013
- Steven Dubovsky, MD
- Psychiatry
Women with bipolar I disorder had higher risk for episodes within 6 weeks of delivery than those with bipolar II disorder or recurrent major depression.- Reviewing:
- Di Florio A et al., JAMA Psychiatry 2013 Feb; 70:168.
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Overlapping Genetic Risk Factors in Psychiatric Disorders Free
- March 11, 2013
- Peter Roy-Byrne, MD
- Psychiatry
Similar SNPs increase risk for schizophrenia, bipolar disorder, depression, autism, and ADHD.
CME Exam- Reviewing:
- Cross-Disorder Group of the Psychiatric Genomics Consortium., Lancet 2013 Feb 28;:
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Reviews of Note
- February 4, 2013
- Psychiatry
Treating functional symptoms with TMS; oxytocin concerns; depression in pregnancy; comorbid substance use and mood disorders; mixed states; another promise of genomic medicine; loss of gray matter in schizophrenia -
Can Imaging Detect Risk for Bipolar Disorder?
- January 28, 2013
- Steven Dubovsky, MD
- Psychiatry
Enlarged gray-matter volumes in the right inferior frontal gyrus were consistently found in two separate analyses.- Reviewing:
- Hajek T et al., Biol Psychiatry 2013 Jan 15; 73:144. Singh MK and Chang KD., Biol Psychiatry 2013 Jan 15; 73:109.
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Adding Moderate-Dose Lithium to Other Bipolar Treatments: Is There a Benefit?
- January 14, 2013
- Joel Yager, MD
- Psychiatry
Symptomatic patients receiving lithium added to optimized personal treatment did no better than patients not taking lithium but had less antipsychotic exposure.- Reviewing:
- Nierenberg AA et al., Am J Psychiatry 2013 Jan; 170:102.
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Endogenous Retroviruses as Contributors to Psychotic Illness?
- January 14, 2013
- Joel Yager, MD
- Psychiatry
A specific human endogenous retrovirus envelope gene may act at the interface of genetic, infectious, and immunological factors in the pathogenesis of schizophrenia and bipolar disorder.- Reviewing:
- Perron H et al., Transl Psychiatry 2012 Dec 4; 2:e201.
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Adjunctive Mifepristone for Cognitive Dysfunction in Bipolar Depression
- January 7, 2013
- Steven Dubovsky, MD
- Psychiatry
In women, a long-term effect on working memory from short-term mifepristone use- Reviewing:
- Watson S et al., Biol Psychiatry 2012 Dec 1; 72:943.
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Adverse Pregnancy Outcomes and Bipolar Disorder Free
- November 19, 2012
- Deborah Cowley, MD
- Psychiatry
The increased risks are independent of treatment for the disorder.- Reviewing:
- Boden R et al., BMJ 2012 Nov 8; 345:e7085.
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Treatment Choices for Resistant Bipolar Disorder
- November 19, 2012
- Jonathan Silver, MD
- Psychiatry
Several options exist, including clozapine.- Reviewing:
- Kemp DE et al., Bipolar Disord 2012 Nov; 14:780. Nielsen J et al., Bipolar Disord 2012 Oct 26;: Poon SH et al., Bipolar Disord 2012 Sep; 14:573.
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Bipolar Disorder, Treated or Not, Linked to Adverse Pregnancy Outcomes Free
- November 9, 2012
- Physician's First Watch
Bipolar disorder is associated with increased risks for adverse pregnancy outcomes, regardless of treatment, according to a BMJ study.Using Swedish national health registries, researchers... -
Cognitive Deficits in Euthymic Patients with Bipolar Disorder
- October 15, 2012
- Deborah Cowley, MD
- Psychiatry
Deficits persist over time and are associated with poor psychosocial functioning.- Reviewing:
- Mora E et al., Psychol Med 2012 Aug 31;:
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Reviews of Note
- October 5, 2012
- Psychiatry
Minimizing psychotherapy dropout; pathophysiology of bipolar disorder; imaging the ADHD brain; cognitive function with methamphetamine use; reversing critical periods of development; growing new parts of the brain -
Duration of Untreated Bipolar Disorder Can Be Long
- September 24, 2012
- Joel Yager, MD
- Psychiatry
Outcomes may worsen with poor detection of bipolar disorder.- Reviewing:
- Drancourt N et al., Acta Psychiatr Scand 2012 Aug 20;:
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Family Psychiatric History Increases Risk for Autism
- July 30, 2012
- Barbara Geller, MD
- Psychiatry
Rates of schizophrenia and bipolar disorder are elevated in first-degree relatives of people with autism spectrum disorders.
CME Exam- Reviewing:
- Sullivan PF et al., Arch Gen Psychiatry 2012 Jul 2;:
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Ketamine for Bipolar Depression Free
- July 9, 2012
- Steven Dubovsky, MD
- Psychiatry
The drug may prove useful acutely in severely depressed patients who need an immediate response.- Reviewing:
- Zarate CA Jr et al., Biol Psychiatry 2012 Jun 1; 71:939.
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Likelihood of Bipolar Outcome Is Elevated with Postpartum Onset of Psychiatric Illness Free
- May 14, 2012
- Steven Dubovsky, MD
- Psychiatry
Women with illness presenting in the first postpartum month are particularly at risk.- Reviewing:
- Munk-Olsen T et al., Arch Gen Psychiatry 2012 Apr; 69:428.
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Alcohol Sensitivity and Mood Disorder
- May 14, 2012
- Barbara Geller, MD
- Psychiatry
Young adults with bipolar features expect more pleasant effects from alcohol intake but have lower “highs” than controls.- Reviewing:
- Yip SW et al., Neuropsychopharmacology 2012 Apr 11;:
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The Bipolar/Schizophrenia Border Continues to Widen
- May 7, 2012
- Steven Dubovsky, MD
- Psychiatry
Shared neurodevelopmental factors may reflect overlapping and genetically determined liabilities to features common to both disorders.- Reviewing:
- Hulshoff Pol HE et al., Arch Gen Psychiatry 2012 Apr; 69:349.
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