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Search for ischemic stroke in all Journal Watch editions
Physician-authored summaries on the latest research on ischemic stroke, editorials on ischemic stroke, and perspectives on ischemic stroke - drawn from the top medical journals.
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You searched for: ischemic stroke
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Tenecteplase for Acute Stroke?
- March 21, 2012
- Seemant Chaturvedi, MD
- Neurology
An investigational drug shows promise in a phase IIB study.- Reviewing:
- Parsons M et al., N Engl J Med 2012 Mar 22; 366:1099.
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A Novel Score to Predict Outcomes of Intravenous Thrombolysis
- March 6, 2012
- Kevin N. Sheth, MD
- Neurology
The DRAGON score shows promise as an easy bedside tool, but further validation is needed before it is used clinically.- Reviewing:
- Strbian D et al., Neurology 2012 Feb 7; 78:427.
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Is Anticoagulation Therapy Safe for Children with Ischemic Stroke?
- January 17, 2012
- David Green, MD, PhD
- Oncology and Hematology
Results from a small observational study suggest that the risk for ACT-associated intracranial hemorrhage is low.- Reviewing:
- Schechter T et al., Blood 2011 Dec 7;:
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Statins After Stroke or TIA: More Evidence of Benefits
- November 22, 2011
- Hooman Kamel, MD
- Neurology
A substudy of the SPARCL trial indicates that patients with stroke or transient ischemic attack benefit from statin therapy regardless of baseline diabetes.- Reviewing:
- Callahan A et al., Arch Neurol 2011 Oct; 68:1245.
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MRI Findings and Recurrent-Stroke Prediction in Young Adults
- September 6, 2011
- Amy Gelfand, MD
- Neurology
Silent brain infarcts noted on MRI after a first ischemic stroke are associated with increased risk for recurrent stroke.- Reviewing:
- Putaala J et al., Neurology 2011 May 17; 76:1742.
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Partial Aortic Occlusion Procedure Is Safe in Patients with Ischemic Stroke
- July 19, 2011
- Brett Cucchiara, MD
- Neurology
Increasing cerebral perfusion with a catheter-based balloon device was safe and possibly beneficial, but only in particular patient subgroups.- Reviewing:
- Shuaib A et al. for the SENTIS Trial Investigators., Stroke 2011 Jun; 42:1680.
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Has Joint Commission Certification of Primary Stroke Centers Affected Outcomes?
- July 12, 2011
- Irene Katzan, MD
- Neurology
Among Medicare beneficiaries, 30-day mortality rates after ischemic stroke, but not 30-day readmission rates, were somewhat better at certified than at noncertified centers.- Reviewing:
- Lichtman JH et al., Neurology 2011 Jun 7; 76:1976.
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Causes of Ischemic Stroke in Young Adults
- June 23, 2011
- Allan S. Brett, MD
- General Medicine
Definite causes were identified in only half of 318 cases.- Reviewing:
- Larrue V et al., Neurology 2011 Jun 7; 76:1983.
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Alteplase Dose for Ischemic Stroke in Very Heavy Patients Free
- June 21, 2011
- Bruce Ovbiagele, MD, MS
- Neurology
Despite a low per-kilogram dose, the current 90-mg maximum dose seems effective, according to data from a large, international thrombolysis registry.- Reviewing:
- Diedler J et al., Stroke 2011 Jun; 42:1615.
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Neurothrombectomy Devices for Acute Ischemic Stroke
- June 7, 2011
- Jeremy Fields, MD, and Helmi Lutsep, MD
- Neurology
Currently available neurothrombectomy devices are associated with high rates of recanalization and relatively low rates of harm, according to a meta-analysis.- Reviewing:
- Baker WL et al., Ann Intern Med 2011 Feb 15; 154:243. Khatri P., Ann Intern Med 2011 Feb 15; 154:285.
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Stroke Center Designation and Mortality Free
- March 1, 2011
- Bruce Ovbiagele, MD, MS
- Neurology
Does treatment at a designated stroke center reduce mortality for patients with acute ischemic stroke?- Reviewing:
- Xian Y et al., JAMA 2011 Jan 26; 305:373.
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Ischemic Stroke Recurrence in Young Adults Free
- February 15, 2011
- Christine Fox, MD
- Neurology
A large study of stroke recurrence rates in young-adult patients- Reviewing:
- Putaala J et al., Ann Neurol 2010 Nov; 68:661.
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HIV and Stroke
- February 9, 2011
- Rajesh T. Gandhi, MD
- Infectious Diseases
The proportion of hospitalized stroke patients who are HIV-infected is increasing; multiple reasons are likely.- Reviewing:
- Ovbiagele B and Nath A., Neurology 2011 Feb 1; 76:444.
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Gene Expression Profiles Predict Stroke Subtypes
- December 7, 2010
- Amy K. Guzik, MD, and Bradford B. Worrall, MD, MSc
- Neurology
Serum biomarkers may one day be useful in distinguishing cardioembolic from large-vessel ischemic stroke.- Reviewing:
- Jickling GC et al., Ann Neurol 2010 Nov; 68:681.
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Predicting Short-Term Risk for Stroke Recurrence
- January 22, 2010
- Richard D. Zane, MD, FAAEM
- Emergency Medicine
A new Web-based risk score based on readily available clinical and imaging information is a good predictor of risk for recurrence.- Reviewing:
- Ay H et al., Neurology 2010 Jan 12; 74:128.
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Expanding the Window for Acute Stroke Treatment
- October 6, 2009
- James S. McKinney, MD
- Neurology
New recommendations from the American Heart Association/American Stroke Association on using t-PA between 3 and 4.5 hours after stroke onset- Reviewing:
- del Zoppo GJ et al., Stroke 2009 Aug; 40:2945.
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Recanalization and Bleeding After IV TPA
- January 6, 2009
- Mark J. Alberts, MD
- Neurology
Recanalization status 2 hours after treatment is associated with risk for symptomatic intracerebral hemorrhage.- Reviewing:
- Saqqur M et al., Neurology 2008 Oct 21; 71:1304. Tanne D and Levine SR., Neurology 2008 Oct 21; 71:1300.
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Cigarette Smoking and Stroke Risk in Young Women
- October 9, 2008
- JoAnne M. Foody, MD
- Women's Health
Stroke risk was substantially higher in current smokers than in never smokers or former smokers and increased sharply with number of cigarettes smoked daily.- Reviewing:
- Bhat VM et al., Stroke 2008 Sep; 39:2439.
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Extending the Time Frame for Alteplase: The ECASS III Trial
- September 24, 2008
- Harlan M. Krumholz, MD, SM
- Cardiology
In patients with acute ischemic stroke, alteplase may be effective up to 4.5 hours after symptom onset.- Reviewing:
- Hacke W et al. for the ECASS Investigators., N Engl J Med 2008 Sep 25; 359:1317.
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Thrombolysis for Stroke Within 4.5 Hours Is Safe and Effective Free
- September 24, 2008
- J. Stephen Bohan, MD, MS, FACP, FACEP
- Emergency Medicine
But still, the sooner treatment is administered, the better!- Reviewing:
- Hacke W et al. for the ECASS Investigators., N Engl J Med 2008 Sep 25; 359:1317. Lyden P., N Engl J Med 2008 Sep 25; 359:1393.
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