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Physician-authored summaries on the latest research on intensive lipid-lowering therapy, editorials on intensive lipid-lowering therapy, and perspectives on intensive lipid-lowering therapy - drawn from the top medical journals.
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New Questions and a Few Answers on Vytorin and Cancer Risks Free
- September 2, 2008
- Physician's First Watch
An analysis published online by the New England Journal of Medicine sheds new light on the cancer risks of intensive lipid-lowering therapy... -
Can LDL Levels Be Too Low?
- November 25, 2005
- Kirsten E. Fleischmann, MD, MPH
- General Medicine
A retrospective analysis suggests that intensive statin therapy resulting in very low LDL levels is safe, but whether such levels should be a target is not clear.
Audio Interview- Reviewing:
- Wiviott SD et al., J Am Coll Cardiol 2005 Oct 18; 46:1411-6.
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All Non–ST-Segment-Elevation Acute Coronary Syndromes to the Cath Lab? Maybe Not
- October 25, 2005
- J. Stephen Bohan, MD, MS, FACP, FACEP
- Emergency Medicine
Dutch researchers compared an early invasive strategy and a selectively invasive strategy in patients with non–ST-segment-elevation acute coronary syndromes (NSTE ACS) and elevated troponin T . . .- Reviewing:
- de Winter RJ et al., N Engl J Med 2005 Sep 15; 353:1095-104.
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Routine vs. Selective Invasive Management for Acute Coronary Syndromes
- September 30, 2005
- Kirsten E. Fleischmann, MD, MPH
- General Medicine
In contrast to previous findings, results of a new randomized study indicate no advantage for a strategy of routine early angiography.- Reviewing:
- de Winter RJ et al., N Engl J Med 2005 Sep 15; 353:1095-104. Boden WE., N Engl J Med 2005 Sep 15; 353:1159-61.
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Statins Do Not Slow Calcific Aortic Stenosis
- July 15, 2005
- Harlan M. Krumholz, MD, SM
- Cardiology
Calcific aortic stenosis (AS) is a progressive form of valvular heart disease for which no preventive therapies exist. Like atherosclerosis, calcific AS is mediated by . . .- Reviewing:
- Cowell SJ et al. for the Scottish Aortic Stenosis and Lipid Lowering Trial, Impact on Regression (SALTIRE) Investigators., N Engl J Med 2005 Jun 9; 352:2389-97. Rosenhek R., N Engl J Med 2005 Jun 9; 352:2441-3.
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MORE EVIDENCE THAT LIPID-LOWERING THERAPY CAN REVERSE CORONARY ATHEROSCLEROSIS.
- November 9, 1990
- ALK
- General Medicine
A recent study of ileal bypass surgery showed that lipid reduction can cause a regression of atherosclerosis (see accession number 901005001). A new study using . . .- Reviewing:
- Loscalzo J., N Engl J Med 1990 Nov 8; 323:
1337 1339 . Brown G et al., N Engl J Med 1990 Nov 8; 323:1289 1298 .
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