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Search for gastroesophageal reflux disease (GERD) in all Journal Watch editions
Physician-authored summaries on the latest research on gastroesophageal reflux disease (GERD), editorials on gastroesophageal reflux disease (GERD), and perspectives on gastroesophageal reflux disease (GERD) - drawn from the top medical journals.
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You searched for: gastroesophageal reflux disease (GERD)
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A Murky Relationship Between GERD and Interstitial Lung Disease
- February 3, 2012
- David A. Johnson, MD
- Gastroenterology
Previous studies document a high prevalence of GERD in patients with idiopathic pulmonary fibrosis but provide no evidence of causality.- Reviewing:
- Hershcovici T et al., Aliment Pharmacol Ther 2011 Dec; 34:1295.
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PPIs Don't Ease Asthma Symptoms in Children with Severe Asthma and Asymptomatic GERD
- February 2, 2012
- David J. Amrol, MD
- General Medicine
In addition, lansoprazole raised the incidence of adverse events.- Reviewing:
- Holbrook JT et al., JAMA 2012 Jan 25; 307:373. Martinez FD., JAMA 2012 Jan 25; 307:406.
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Diagnosing Gastroenterological Causes of Noncardiac Chest Pain Free
- December 22, 2011
- David A. Johnson, MD
- Gastroenterology
Endoscopy and pH tests should be used to confirm GERD status to guide decisions on treatment with PPIs and the need for further diagnostic testing.
CME Exam- Reviewing:
- Kahrilas PJ et al., Gut 2011 Nov; 60:1473.
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Eosinophilic Esophagitis Should Not Be Diagnosed by Histology Alone
- August 12, 2011
- David A. Johnson, MD
- Gastroenterology
Response to high-dose proton-pump inhibitors suggests diagnoses other than EoE.
CME Exam- Reviewing:
- Molina-Infante J et al., Clin Gastroenterol Hepatol 2011 Feb; 9:110.
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Esomeprazole vs. Surgery for Chronic GERD Free
- May 20, 2011
- David A. Johnson, MD
- Gastroenterology
At 5 years, remission rates were high for PPI-responsive patients receiving either treatment, although remission was slightly higher for esomeprazole than surgery.
CME Exam- Reviewing:
- Galmiche J-P et al., JAMA 2011 May 18; 305:1969.
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Use of Proton-Pump Inhibitors in Infants and Children
PPIs are not effective in infants, but this analysis suggests that a trial of PPIs might be warranted in children and adolescents with gastroesophageal reflux.- Reviewing:
- van der Pol RJ et al., Pediatrics 2011 May; 127:925.
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Looking for Reflux with MII: How Useful Is It?
Multichannel intraluminal impedance results rarely changed management decisions.- Reviewing:
- Rosen R et al., J Pediatr Gastroenterol Nutr 2011 Apr; 52:404.
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Esophageal Adenocarcinoma in Populations with Gastroesophageal Reflux Disease
- April 22, 2011
- David A. Johnson, MD
- Gastroenterology
Incidence of EAC in patients with GERD was very low overall, especially among men younger than 50 and women at any age.
CME Exam- Reviewing:
- Rubenstein JH et al., Am J Gastroenterol 2011 Feb; 106:254. Shaheen NJ., Am J Gastroenterol 2011 Feb; 106:261.
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Proton-Pump Inhibitor Therapy for Postnasal Drainage?
- November 19, 2010
- David A. Johnson, MD
- Gastroenterology
Lansoprazole outperformed placebo, reviving old questions about silent gastroesophageal reflux disease and extraesophageal reflux.- Reviewing:
- Vaezi MF et al., Gastroenterology 2010 Aug 27;:
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Lesogaberan for Gastroesophageal Reflux Disease?
- August 20, 2010
- David A. Johnson, MD
- Gastroenterology
The jury is still out on this alternate approach.- Reviewing:
- Boeckxstaens GE et al., Gastroenterology 2010 Aug; 139:409. Falk GW., Gastroenterology 2010 Aug; 139:377.
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Another Trial of Proton-Pump Inhibitor Therapy for Asthma
- May 25, 2010
- Allan S. Brett, MD
- General Medicine
Esomeprazole provided no clinically important benefits.- Reviewing:
- Kiljander TO et al., Am J Respir Crit Care Med 2010 May 15; 181:1042.
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Is It Eosinophilic Esophagitis or Reflux Disease?
- March 5, 2010
- David A. Johnson, MD
- Gastroenterology
A predictive model reliably distinguished EoE from GERD.
CME Exam- Reviewing:
- Dellon ES et al., Clin Gastroenterol Hepatol 2009 Dec; 7:1305.
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Why Won’t This Child Eat?
A careful history can help differentiate organic from behavioral feeding problems.- Reviewing:
- Levy Y et al., J Pediatr Gastroenterol Nutr 2009 Mar; 48:355.
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Laparoscopic Fundoplication for Chronic GERD
- January 27, 2009
- Paul S. Mueller, MD, MPH, FACP
- General Medicine
At 1 year, fundoplication resulted in less need for reflux medications and better quality of life than did medical management, but its cost-effectiveness is still to be determined.- Reviewing:
- Grant AM et al., BMJ 2008 Dec 15; 337:a2664.
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Guidelines on GERD Management Issued Free
- October 22, 2008
- Physician's First Watch
The American Gastroenterological Association has released guidelines on the management of gastroesophageal reflux disease (GERD) in Gastroenterology. Among the highlights: Proton pump inhibitors (PPIs) are... -
Heartburn from Estrogen?
- October 9, 2008
- Wendy S. Biggs, MD
- Women's Health
Users of hormone therapy, the selective estrogen-receptor modulator raloxifene, or over-the-counter soy estrogen products were more likely to report GERD symptoms than were never users.- Reviewing:
- Jacobson BC et al., Arch Intern Med 2008 Sep 8; 168:1798.
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FDA Approves Nexium for Young Children Free
Children older than 1 year with documented GERD or esophagitis now have another PPI choice. -
Empirical Esomeprazole vs. Endoscopy-Guided Treatment for GERD
- March 11, 2008
- Paul S. Mueller, MD, MPH, FACP
- General Medicine
Empirical treatment of GERD without alarm symptoms was as effective as and less expensive than endoscopy-guided treatment.- Reviewing:
- Giannini EG et al., Am J Gastroenterol 2008 Feb; 103:267.
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Abdominal Circumference and BE
- August 30, 2007
- David A. Johnson, MD
- Gastroenterology
In a case-control study, larger abdominal circumference (adjusted for BMI) was associated modestly with greater risk for Barrett esophagus.- Reviewing:
- Corley DA et al., Gastroenterology 2007 Jul; 133:34-41.
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Obesity, Abdominal Diameter, and GERD Free
- August 10, 2007
- David A. Johnson, MD
- Gastroenterology
At least in white patients, the amount of visceral adipose tissue is related to the severity of GERD symptoms.- Reviewing:
- El-Serag HB et al., Gut 2007 Jun; 56:749-55. Corley DA et al., Gut 2007 Jun; 56:756-62.
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