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Search for dementia in all Journal Watch editions
Physician-authored summaries on the latest research on dementia, editorials on dementia, and perspectives on dementia - drawn from the top medical journals.
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Dementia Outpaces Cancer in Financial Burden to United States
- April 30, 2013
- Brandy R. Matthews, MD
- Neurology
A model that includes costs of informal care estimates that more than US$150 billion was spent in 2010.- Reviewing:
- Hurd MD et al., N Engl J Med 2013 Apr 4; 368:1326.
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Midlife Cardiorespiratory Fitness Might Attenuate Later-Life Dementia
- March 19, 2013
- Jamaluddin Moloo, MD, MPH
- General Medicine
Later dementia was less common among people who were more fit before age 65.- Reviewing:
- DeFina LF et al., Ann Intern Med 2013 Feb 5; 158:162.
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Poor Physical Performance Associated with Dementia, Again
- November 13, 2012
- Brandy R. Matthews, MD
- Neurology
The “oldest old” are more likely to have dementia if they have physical impairments.- Reviewing:
- Bullain SS et al., Arch Neurol 2012 Oct 22;:
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New Benzodiazepine Use Is Associated with Risk for Dementia
- November 6, 2012
- Paul S. Mueller, MD, MPH, FACP
- General Medicine
Risk rose by about 60% among elders in whom treatment with these drugs was initiated.- Reviewing:
- de Gage SB et al., BMJ 2012 Sep 27; 345:e6231.
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CSF Panel Analysis for Diagnosis of Dementia and Parkinsonian Disorders
- September 18, 2012
- Michael S. Okun, MD
- Neurology
A panel of five markers was useful in distinguishing among various dementing and parkinsonian diseases in a clinic-based patient sample.- Reviewing:
- Hall S et al., Arch Neurol 2012 Aug 27;:
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Antipsychotics and Myocardial Infarction in Dementia Patients
- May 1, 2012
- Brandy R. Matthews, MD
- Neurology
The risk for MI was significantly elevated in the first month after initiation of antipsychotics in dementia patients already treated with cholinesterase inhibitors.- Reviewing:
- Pariente A et al., Arch Intern Med 2012 Apr 23; 172:648.
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Antidepressants in Dementia: To Stop or Not? Free
- April 13, 2012
- Jonathan Silver, MD
- Psychiatry
Some patients have increased symptoms after SSRI discontinuation, but most do well.- Reviewing:
- Bergh S et al., BMJ 2012 Mar 9; 344:e1566.
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“Silent” Cerebral Emboli May Hasten Progression of Dementia Free
- April 5, 2012
- Allan S. Brett, MD
- General Medicine
This finding was noted both in patients with Alzheimer disease and those with vascular dementia.- Reviewing:
- Purandare N et al., Am J Psychiatry 2012 Mar 1; 169:300. Doraiswamy PM., Am J Psychiatry 2012 Mar 1; 169:251.
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An Effective Treatment for Dementia with Lewy Bodies
- March 5, 2012
- Jonathan Silver, MD
- Psychiatry
Donepezil improved cognition and behavior.- Reviewing:
- Mori E et al., Ann Neurology 2012 Feb 8;:
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Dementia Associated with Increased Rate of Hospitalization
- February 21, 2012
- Helen Kao, MD
- Neurology
In a prospective cohort study, elders who developed dementia had higher rates of hospitalization — particularly for conditions potentially treatable in outpatient settings — than those who didn't develop dementia.- Reviewing:
- Phelan EA et al., JAMA 2012 Jan 11; 307:165.
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Is Memantine Effective for Dementia in Patients with Down Syndrome?
- February 21, 2012
- Jaime Toro, MD
- Neurology
Apparently not, according to a randomized, double-blind, placebo-controlled trial- Reviewing:
- Hanney M et al., Lancet 2012 Feb 11; 379:528.
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Another Screening Test for Dementia
- February 9, 2012
- Allan S. Brett, MD
- General Medicine
A simple “visual association” test was quite sensitive and specific.- Reviewing:
- Fuchs A et al., J Am Geriatr Soc 2012 Jan; 60:130.
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Antipsychotics Vary in Mortality Risk in Dementia Patients
- February 6, 2012
- Joel Yager, MD
- Psychiatry
Haloperidol had the highest 6-month mortality rate; quetiapine, the lowest.- Reviewing:
- Kales HC et al., Am J Psychiatry 2012 Jan; 169:71.
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Altered Circadian Rhythms Are Associated with Dementia
- January 9, 2012
- Jonathan Silver, MD
- Psychiatry
But are they a cause or an effect?- Reviewing:
- Tranah GJ et al., Ann Neurol 2011 Nov; 70:722. Lim ASP and Saper CB., Ann Neurol 2011 Nov; 70:677.
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Medicare Costs of Advanced Dementia
- February 1, 2011
- Liana S. Rosenthal, MD, and E. Ray Dorsey, MD, MBA
- Neurology
Hospitalizations and hospice care drive Medicare expenditures for nursing home residents with advanced dementia.- Reviewing:
- Goldfeld KS et al., Arch Intern Med 2011 Jan 10;:
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Hormone Therapy and Dementia Risk: A Critical Window? Free
- January 4, 2011
- Brandy R. Matthews, MD
- Neurology
A prospective cohort study reveals a decreased risk for dementia in women taking HT in midlife but an increased risk for those taking HT in later life.- Reviewing:
- Whitmer RA et al., Ann Neurol 2010 Nov 12;:
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To Prevent Dementia, Is Timing Everything?
- December 20, 2010
- Jonathan Silver, MD
- Psychiatry
Clinical and preclinical evidence of a critical window for hormone therapy to prevent dementia- Reviewing:
- Whitmer RA et al., Ann Neurol 2010 Nov 12;: Smith CC et al., Proc Natl Acad Sci U S A 2010 Nov 9; 107:19543.
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Survival Prediction in Patients with Advanced Dementia
- November 24, 2010
- Thomas L. Schwenk, MD
- General Medicine
Structured clinical assessment outperformed hospice eligibility guidelines.- Reviewing:
- Mitchell SL et al., JAMA 2010 Nov 3; 304:1929.
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Dementia Associated with Heavy Smoking in Midlife Free
- November 16, 2010
- Brandy R. Matthews, MD
- Neurology
Midlife cigarette smoking of two packs per day or more portends an elevated risk for overall dementia, Alzheimer disease, and vascular dementia in later life.- Reviewing:
- Rusanen M et al., Arch Intern Med 2010 Oct 25;:
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Practice Parameter: Assessing and Managing Driving Risk in Dementia
- October 19, 2010
- Germaine L. Odenheimer, MD
- Neurology
An update on the evidence for factors that predict increased driving risk- Reviewing:
- Iverson DJ et al., Neurology 2010 Apr 20; 74:1316.
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