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Search for bone pain in all Journal Watch editions
Physician-authored summaries on the latest research on bone pain, editorials on bone pain, and perspectives on bone pain - drawn from the top medical journals.
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You searched for: bone pain
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Voriconazole Associated with High Serum Fluoride and Bone Disease
- October 16, 2012
- David Green, MD, PhD
- Oncology and Hematology
Patients with hematologic malignancies who received long-term voriconazole developed bone pain and periostitis.- Reviewing:
- Gerber B et al., Blood 2012 Sep 20; 120:2390.
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Do Symptoms Correlate with Degree of Hypercalcemia in Primary Hyperparathyroidism?
- October 13, 2011
- Allan S. Brett, MD
- General Medicine
Not in this large cohort- Reviewing:
- Bargren AE et al., J Am Coll Surg 2011 Sep; 213:410.
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Schnitzler Syndrome: A Review of 20 Patients
- June 15, 2012
- Jeffrey P. Callen, MD
- Dermatology
Nine patients developed a malignancy over 2 to 13 years; a neutrophilic, perivascular, infiltrative process was the most frequent histopathological presentation.- Reviewing:
- Sokumbi O et al., J Am Acad Dermatol 2012 May 22;:
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Denosumab Delays Development of Bone Metastases in Prostate Cancer
- December 20, 2011
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
Denosumab recipients achieved a 4.2-month improvement in bone metastasis–free survival compared with placebo recipients.- Reviewing:
- Smith MR et al., Lancet 2011 Nov 16;: Logothetis CJ., Lancet 2011 Nov 16;:
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ASCO 2011 Report: Genitourinary Cancer Free
The management of advanced renal cell cancer (RCC) has evolved into a sequential paradigm since the current generation of agents targeting the vascular endothelial growth . . . -
Denosumab Approved for Cancer-Related Bone Injury Free
- November 22, 2010
- Physician's First Watch
The FDA has approved denosumab (marketed as Xgeva) for the prevention of fracture and bone pain in patients with cancer that has metastasized to the... -
Adding Zoledronic Acid to Endocrine Therapy for Premenopausal Breast Cancer Free
- February 11, 2009
- Andrew M. Kaunitz, MD
- Women's Health
European trial results suggest that adding IV bisphosphonate therapy improves outcomes.- Reviewing:
- Gnant M et al., N Engl J Med 2009 Feb 12; 360:679.
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Zoledronic Acid for Preventing Bone Loss in Young Breast Cancer Patients
- October 23, 2008
- Andrew M. Kaunitz, MD
- Women's Health
Intravenous bisphosphonate prevented loss of BMD associated with chemotherapy.- Reviewing:
- Hershman DL et al., J Clin Oncol 2008 Oct 10; 26:4739.
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Maintaining Bone Mass in Premenopausal Breast Cancer Patients: How Effective Is Zoledronic Acid?
- September 25, 2008
- Andrew M. Kaunitz, MD
- Women's Health
IV bisphosphonate provided long-term protection against BMD loss in premenopausal women receiving adjuvant endocrine therapy.- Reviewing:
- Gnant M et al., Lancet Oncol 2008 Sep; 9:840.
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Lenalidomide for Relapsed Chronic Lymphocytic Leukemia Patients Free
- July 8, 2008
- Michael E. Williams, MD
- Oncology and Hematology
Lenalidomide, given as a continuous daily oral dose, showed antitumor activity in one third of heavily pretreated CLL patients.- Reviewing:
- Ferrajoli A et al., Blood 2008 Jun 1; 111:5291.
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Vitamin D Compounds Have Uncertain Benefit in Kidney Disease
- January 17, 2008
- Richard Saitz, MD, MPH, FACP, FASAM
- General Medicine
Results of a meta-analysis indicate that efficacy is unproven.- Reviewing:
- Palmer SC et al., Ann Intern Med 2007 Dec 18; 147:840. Tonelli M., Ann Intern Med 2007 Dec 18; 147:880.
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Bisphosphonates Linked to Severe Bone and Muscle Pain, FDA Warns Free
- January 8, 2008
- Physician's First Watch
Bisphosphonates may cause "severe and sometimes incapacitating" musculoskeletal pain, the FDA warned on Monday. Patients may develop intense pain within days, months, or years of... -
Aromatase-Inhibitor–Induced Joint Complaints: An Underappreciated Problem?
- October 16, 2007
- William J. Gradishar, MD
- Oncology and Hematology
Joint complaints are common among women who receive AIs.- Reviewing:
- Crew KD et al., J Clin Oncol 2007 Sep 1; 25:3877.
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Adjuvant Therapy for ER-Positive Breast Cancer: Shaping the Role of Aromatase Inhibitors
- August 16, 2007
- Andrew M. Kaunitz, MD
- Women's Health
Two years of tamoxifen followed by a switch to anastrozole is an effective adjuvant therapy for ER-positive breast cancer.- Reviewing:
- Kaufmann M et al., J Clin Oncol 2007 Jul 1; 25:2664-70. Lin NU and Winer EP., J Clin Oncol 2007 Jul 1; 25:2639-41.
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Intravenous Zoledronic Acid for Paget Disease
- September 20, 2005
- Allan S. Brett, MD
- General Medicine
Paget disease of bone, characterized by increased bone turnover, is relatively common in older populations. It often is discovered incidentally at early asymptomatic stages, but . . .- Reviewing:
- Reid IR et al., N Engl J Med 2005 Sep 1; 353:898-908.
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A Positive Epstein-Barr Virus PCR in the CSF in an HIV-Infected Patient: When the Pathogen Does Not Match the Syndrome
- February 1, 2004
- Elizabeth R. Jenny-Avital, MD, Christina M. Marra, MD, Elizabeth R. Jenny-Avital, MD, and Christina M. Marra, MD
- HIV/AIDS
Eduard is a 56-year-old man who tested HIV-positive in 1991, after his wife tested positive during pregnancy. His CD4 count, initially 192 cells/mm3, . . . -
Vitamin D Deficiency: An Explanation for Nonspecific Aches and Pains?
- January 9, 2004
- Allan S. Brett, MD
- General Medicine
Consider 2 clinical observations: (1) Primary care physicians often encounter patients with unexplained musculoskeletal complaints, and (2) studies have documented a surprisingly high prevalence of . . .
Audio Interview- Reviewing:
- Plotnikoff GA and Quigley JM., Mayo Clin Proc 2003 Dec; 78:1463-70. Holick MF., Mayo Clin Proc 2003 Dec; 78:1457-9.
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Managing the Risks of Corticosteroid Therapy
- May 1, 1998
- Sandra K Knowles, BScPharm, and Neil H Shear, MD, Sunnybrook Health Science Centre, University of Toronto
- Dermatology
Systemic corticosteroids are powerful tools that enable dermatologists to treat a large spectrum of diseases. However, the potential benefits of systemic glucocorticoids must be carefully . . . -
Breast Examination Among Older Women
- December 1, 1997
- MA Shepard
- Women's Health
Breast cancer is most common in older women, yet these women may not be routinely offered breast examinations. These British researchers interviewed 100 hospitalized women . . .- Reviewing:
- Haigney E et al., BMJ 1997 Oct 25; 315:
1058 1059 .
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Pamidronate Reduces Bone Complications of Breast Cancer
- February 1, 1997
- SD Gharib
- Women's Health
For patients with advanced breast cancer, bone pain and fractures are among the worst complications and severely impair quality of life. Pamidronate, a bisphosphonate that . . .- Reviewing:
- Hortobagyi GN et al., N Engl J Med 1996 Dec 12; 335:
1785 1791 .
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