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Search for bone loss in all Journal Watch editions
Physician-authored summaries on the latest research on bone loss, editorials on bone loss, and perspectives on bone loss - drawn from the top medical journals.
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You searched for: bone loss
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Vitamin D Levels and Bone Loss in Older Men
- August 13, 2009
- Allan S. Brett, MD
- General Medicine
In men older than 75, 25(OH)D levels lower than 20 ng/mL were associated with accelerated bone loss.- Reviewing:
- Ensrud KE et al., J Clin Endocrinol Metab 2009 Aug; 94:2773.
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Oral Raloxifene, Transdermal Estradiol Similar at Preserving Bone Density
- June 11, 2009
- Diane E. Judge, APN/CNP
- Women's Health
Postmenopausal users of these two drugs had similarly high rates of bone density preservation and few serious side effects.- Reviewing:
- Schaefers M et al., Menopause 2009 May/Jun; 16:559.
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“Microdose” Transdermal Estradiol: As Effective as Raloxifene in Preventing Bone Loss?
- June 9, 2009
- Robert W. Rebar, MD
- General Medicine
Even very low doses of estrogen can help prevent bone loss.- Reviewing:
- Schaefers M et al., Menopause 2009 May/Jun; 16:559.
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Zoledronic Acid for Preventing Bone Loss in Young Breast Cancer Patients
- October 23, 2008
- Andrew M. Kaunitz, MD
- Women's Health
Intravenous bisphosphonate prevented loss of BMD associated with chemotherapy.- Reviewing:
- Hershman DL et al., J Clin Oncol 2008 Oct 10; 26:4739.
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Alendronate’s Effect on Bone Loss in Men Treated with Hormonal Therapy for Prostate Cancer Free
- April 2, 2007
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
Compared with placebo, an oral bisphosphonate significantly improved BMD and lessened bone turnover in men who were receiving ADT.- Reviewing:
- Greenspan SL et al., Ann Intern Med 2007 Mar 20; 146:416-24.
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How Depression Causes a Weak Leg to Stand On Free
- December 4, 2006
- Jonathan Silver, MD
- Psychiatry
This animal study suggests that depression might be a treatable risk factor for osteoporosis.- Reviewing:
- Yirmiya R et al., Proc Natl Acad Sci U S A 2006 Nov 7; 103:16876-81.
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Bone Loss in Patients with Liver Disease
- March 12, 2002
- Kenneth D. Flora, MD
- Gastroenterology
About 30% of patients with chronic liver disease have osteoporosis -- this rate is twice that found in the general population. The pathophysiology for this . . .- Reviewing:
- Ormarsdottir S et al., Eur J Gastroenterol Hepatol 2002 Jan; 14:43-8.
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Duration of Preventive Therapy for Menopausal Bone Loss
- January 18, 2000
- R Saitz
- General Medicine
Alendronate can prevent menopausal bone loss and fractures, but long-term efficacy and optimal duration of use are unknown. In this international study supported by the . . .- Reviewing:
- Ravn P et al., Ann Intern Med 1999 Dec 21; 131:
935 942 .
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Discovery of a Critical Immune Mediator of Joint Destruction and Bone Loss
- December 3, 1999
- AL Komaroff
- General Medicine
The joint destruction seen in rheumatoid arthritis (RA) is known to be immunologically mediated, but which molecules are critical to the process has been unclear. . . .- Reviewing:
- Kong Y-Y et al., Nature 1999 Nov 18; 402:
304 309 .
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Risedronate Prevents Steroid-Induced Bone Loss
- November 23, 1999
- AS Brett
- General Medicine
Several recent studies have shown that bisphosphonate drugs prevent bone loss associated with corticosteroid therapy (see JW Aug 15, 1998, p.130, accession number 980804004, and . . .- Reviewing:
- Cohen S et al., Arthritis Rheum 1999 Nov; 42:
2309 2318 .
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Ultra-Low-Dose Vaginal Estrogen May Prevent Bone Loss
- October 1, 1997
- PJA Hillard
- Women's Health
The minimum dose of estrogen that prevents bone loss in postmenopausal women has not been determined. This randomized study examined forearm bone density in 30 . . .- Reviewing:
- Naessen T et al., Am J Obstet Gynecol 1997 Jul; 177:
115 119 .
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VERY LOW-DOSE ESTROGEN MAY PREVENT BONE LOSS.
- August 22, 1997
- DM Harper
- General Medicine
The minimum dose of estrogen to prevent bone loss in postmenopausal women has not been established. This study assessed whether an ultralow dose of estradiol . . .- Reviewing:
- Naessen T et al., Am J Obstet Gynecol 1997 Jul; 177:
115 119 .
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Calcium May Reverse Corticosteroid-Induced Bone Loss
- February 1, 1997
- CD Mulrow
- Women's Health
Long-term, low-dose corticosteroid use is associated with osteoporosis and an increased risk of vertebral fracture. This double-blind trial evaluated whether calcium and vitamin D supplementation . . .- Reviewing:
- Buckley LM et al., Ann Intern Med 1996 Dec 15; 125:
961 968 .
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Vitamin D Prevents Bone Loss in Elderly Women
- June 1, 1995
- AS Brett
- Dermatology
Several studies suggest that combined vitamin D and calcium supplementation slows bone loss in elderly women. This trial assessed whether vitamin D alone has the . . .- Reviewing:
- Ooms ME et al., J Clin Endocrinol Metab 1995 Apr; 80:
1052 1058 .
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VITAMIN D PREVENTS BONE LOSS IN ELDERLY WOMEN.
- May 5, 1995
- AS Brett
- General Medicine
Several studies suggest that combined vitamin D and calcium supplementation slows bone loss in elderly women. This trial assessed whether vitamin D alone has the . . .- Reviewing:
- Ooms ME, et al., J Clin Endocrinol Metab 1995 Apr; 80:
1052 1058 .
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Triple Therapy for Steroid-Induced Bone Loss
- October 1, 1994
- CD Mulrow
- Dermatology
Osteoporosis is a serious consequence of chronic oral steroid use. This trial in Germany evaluated whether the combination of calcium, vitamin D, and the diphosphonate . . .- Reviewing:
- Worth H et al., Am J Respir Crit Care Med 1994 Aug; 150:
394 397 .
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TRIPLE THERAPY FOR STEROID-INDUCED BONE LOSS.
- September 2, 1994
- CD Mulrow
- General Medicine
Osteoporosis is a serious consequence of chronic oral steroid use. This trial in Germany evaluated whether the combination of calcium, vitamin D, and the diphosphonate . . .- Reviewing:
- Worth H et al., Am J Respir Crit Care Med 1994 Aug; 150:
394 397 .
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More Evidence That Calcium Slows Bone Loss
- April 1, 1993
- ALK
- Dermatology
Studies have shown convincingly that calcium supplementation can prevent bone loss in postmenopausal women with low dietary intakes of calcium. A new study finds benefit . . .- Reviewing:
- Reid IR et al., N Engl J Med 1993 Feb 18; 328:
460 464 . Heaney RP., N Engl J Med 1993 Feb 18; 328:503 505 .
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MORE EVIDENCE THAT CALCIUM SLOWS BONE LOSS AFTER MENOPAUSE.
- March 2, 1993
- ALK
- General Medicine
Studies have shown convincingly that calcium supplementation can prevent bone loss in postmenopausal women with low dietary intake of calcium. A new study finds benefit . . .- Reviewing:
- Heaney RP., N Engl J Med 1993 Feb 18; 328:
503 505 . Reid IR et al., N Engl J Med 1993 Feb 18; 328:460 464 .
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DIETARY CALCIUM DOES NOT INFLUENCE POSTMENOPAUSAL BONE LOSS.
- July 29, 1988
- HGA
- General Medicine
These investigators studied the effect of dietary calcium on bone loss in 59 healthy postmenopausal women, most within five years of menopause. The women were . . .- Reviewing:
- Stevenson J C; Whitehead M I; Padwick M et al., BMJ 1988 Jul 2; 297:
15 17 .
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