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Search for bipolar disorder in all Journal Watch editions
Physician-authored summaries on the latest research on bipolar disorder, editorials on bipolar disorder, and perspectives on bipolar disorder - drawn from the top medical journals.
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You searched for: bipolar disorder
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Functional Remediation for Bipolar Disorders
- April 8, 2013
- Joel Yager, MD
- Psychiatry
In a 21-week, multisite study, add-on functional remediation improved psychosocial functioning more than treatment as usual but not more than psychoeducation.- Reviewing:
- Torrent C et al., Am J Psychiatry 2013 Mar 20;:
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Can Imaging Detect Risk for Bipolar Disorder?
- January 28, 2013
- Steven Dubovsky, MD
- Psychiatry
Enlarged gray-matter volumes in the right inferior frontal gyrus were consistently found in two separate analyses.- Reviewing:
- Hajek T et al., Biol Psychiatry 2013 Jan 15; 73:144. Singh MK and Chang KD., Biol Psychiatry 2013 Jan 15; 73:109.
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Adding Moderate-Dose Lithium to Other Bipolar Treatments: Is There a Benefit?
- January 14, 2013
- Joel Yager, MD
- Psychiatry
Symptomatic patients receiving lithium added to optimized personal treatment did no better than patients not taking lithium but had less antipsychotic exposure.- Reviewing:
- Nierenberg AA et al., Am J Psychiatry 2013 Jan; 170:102.
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Endogenous Retroviruses as Contributors to Psychotic Illness?
- January 14, 2013
- Joel Yager, MD
- Psychiatry
A specific human endogenous retrovirus envelope gene may act at the interface of genetic, infectious, and immunological factors in the pathogenesis of schizophrenia and bipolar disorder.- Reviewing:
- Perron H et al., Transl Psychiatry 2012 Dec 4; 2:e201.
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Adverse Pregnancy Outcomes and Bipolar Disorder Free
- November 19, 2012
- Deborah Cowley, MD
- Psychiatry
The increased risks are independent of treatment for the disorder.- Reviewing:
- Boden R et al., BMJ 2012 Nov 8; 345:e7085.
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Treatment Choices for Resistant Bipolar Disorder
- November 19, 2012
- Jonathan Silver, MD
- Psychiatry
Several options exist, including clozapine.- Reviewing:
- Kemp DE et al., Bipolar Disord 2012 Nov; 14:780. Nielsen J et al., Bipolar Disord 2012 Oct 26;: Poon SH et al., Bipolar Disord 2012 Sep; 14:573.
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Duration of Untreated Bipolar Disorder Can Be Long
- September 24, 2012
- Joel Yager, MD
- Psychiatry
Outcomes may worsen with poor detection of bipolar disorder.- Reviewing:
- Drancourt N et al., Acta Psychiatr Scand 2012 Aug 20;:
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Family Psychiatric History Increases Risk for Autism
- July 30, 2012
- Barbara Geller, MD
- Psychiatry
Rates of schizophrenia and bipolar disorder are elevated in first-degree relatives of people with autism spectrum disorders.
CME Exam- Reviewing:
- Sullivan PF et al., Arch Gen Psychiatry 2012 Jul 2;:
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The Bipolar/Schizophrenia Border Continues to Widen
- May 7, 2012
- Steven Dubovsky, MD
- Psychiatry
Shared neurodevelopmental factors may reflect overlapping and genetically determined liabilities to features common to both disorders.- Reviewing:
- Hulshoff Pol HE et al., Arch Gen Psychiatry 2012 Apr; 69:349.
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Anxiety Increases Impulsivity in Patients with Mood Disorders
- April 9, 2012
- Deborah Cowley, MD
- Psychiatry
Knowing this link can help clinicians who are assessing patients' risks for impulsive behaviors and suicidality.- Reviewing:
- Bellani M et al., J Psychiatr Res 2012 Feb 13;:
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Antiepileptics May Not Elevate Suicide Risk in Patients with Bipolar Disorder Free
- January 23, 2012
- Joel Yager, MD
- Psychiatry
A 30-year observational study showed no rise in risk for suicidal behaviors when antiepileptic medications were used.- Reviewing:
- Leon AC et al., Am J Psychiatry 2011 Dec 15;:
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Difficult-to-Treat Depressed Patients May Be Bipolar
- January 23, 2012
- Peter Roy-Byrne, MD
- Psychiatry
Results based on analyses of a large national database validate clinician impressions that medication-nonresponsive depressed patients may have bipolar illness, often with atypical manifestations.- Reviewing:
- Li C-T et al., Br J Psychiatry 2012 Jan; 200:45.
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Mortality Gap Widening for People with Bipolar Disorder or Schizophrenia
- October 6, 2011
- Paul S. Mueller, MD, MPH, FACP
- General Medicine
Adverse lifestyle factors and antipsychotic medications might be contributing factors.- Reviewing:
- Hoang U et al., BMJ 2011 Sep 13; 343:d5422.
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Lithium or Valproate for Preventing Suicidal Behavior in Patients with Bipolar Disorder?
- August 22, 2011
- Joel Yager, MD
- Psychiatry
The two mood stabilizers yielded similar rates of suicidal behaviors and events.- Reviewing:
- Oquendo MA et al., Am J Psychiatry 2011 Jul 18;:
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More Insight into the Pathophysiology of Bipolar Disorder
- April 4, 2011
- Steven Dubovsky, MD
- Psychiatry
A polymorphism in some patients contributes to the well-characterized altered calcium ion signaling in bipolar disorder, which may become a new research focus.- Reviewing:
- Machado-Vieira R et al., Biol Psychiatry 2011 Feb 15; 69:344.
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Illness Course in Women with Bipolar Disorder Free
- March 14, 2011
- Joel Yager, MD
- Psychiatry
Premenstrual exacerbations are associated with a more difficult course of bipolar illness.
CME Exam- Reviewing:
- Dias RS et al., Am J Psychiatry 2011 Feb 15;:
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Does Bipolar Disorder Contribute to Violence?
- November 1, 2010
- Steven Dubovsky, MD
- Psychiatry
No, but substance abuse does.
CME Exam- Reviewing:
- Fazel S et al., Arch Gen Psychiatry 2010 Sep; 67:931.
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Bipolar Disorder and Schizophrenia — Both Bad for Your Brain
- August 9, 2010
- Steven Dubovsky, MD
- Psychiatry
Affected brain regions are associated with executive function, other cognitive processes, and psychosis.- Reviewing:
- Rimol LM et al., Biol Psychiatry 2010 Jul 1; 68:41.
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Gender Matters in the Course of Bipolar Illness
- July 2, 2010
- Joel Yager, MD
- Psychiatry
Higher rates of both rapid cycling and anxiety disorders among bipolar women help to account for their greater rates of depression.- Reviewing:
- Altshuler LL et al., Am J Psychiatry 2010 Jun; 167:708.
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Bipolar Disorder plus Antisocial Personality Disorder: An Impulsive Storm
- June 7, 2010
- Joel Yager, MD
- Psychiatry
Talk about impulsivity! Comorbid bipolar disorder and antisocial personality disorder- Reviewing:
- Swann AC et al., Acta Psychiatr Scand 2010 Jun; 121:453.
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