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Search for beta-blockers in all Journal Watch editions
Physician-authored summaries on the latest research on beta-blockers, editorials on beta-blockers, and perspectives on beta-blockers - drawn from the top medical journals.
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You searched for: beta-blockers
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Early Beta-Blocker Administration Is Associated with Better Survival After STEMI
- April 12, 2013
- Kristi L. Koenig, MD, FACEP, FIFEM
- Emergency Medicine
Probability of death after 48 hours was 11% with immediate treatment versus 19% with delayed treatment.- Reviewing:
- Hirschl MM et al., Crit Care Med 2013 Mar 29;:
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Beta-Blockers and CAD: Think Treatment, Not Prevention Free
- October 2, 2012
- Harlan M. Krumholz, MD, SM
- Cardiology
In a registry study, the agents did not reduce the risk for events in patients with — or at risk for — stable coronary artery disease.- Reviewing:
- Bangalore S et al. for the REACH Registry Investigators., JAMA 2012 Oct 3; 308:1340.
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Outcomes in Cirrhotic Patients with Variceal Bleeding Despite Primary Prophylaxis with a β-Blocker
- June 22, 2012
- Atif Zaman, MD, MPH
- Gastroenterology
Even with the addition of endoscopic band ligation, such patients are at increased risk for recurrent bleeding and death.- Reviewing:
- de Souza AR et al., Clin Gastroenterol Hepatol 2012 Jun; 10:670.
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Perioperative β-Blockade in Long-Term Users of β-Blockers
- June 21, 2012
- Allan S. Brett, MD
- General Medicine
An observational study supports continuing these drugs perioperatively.- Reviewing:
- Kwon S et al., Arch Surg 2012 May; 147:467.
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Higher β-Blocker Doses Lead to Better Outcomes in Heart Failure Patients
- May 22, 2012
- Kirsten E. Fleischmann, MD, MPH
- General Medicine
Titrating doses to higher levels, as tolerated, seems reasonable.- Reviewing:
- Fiuzat M et al., J Am Coll Cardiol 2012 Apr 18;:
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Beta-Blockers as Breast Cancer Therapy?
- June 28, 2011
- William J. Gradishar, MD
- Oncology and Hematology
Two studies suggest beneficial effects on breast cancer recurrence and survival, but many questions remain.- Reviewing:
- Melhem-Bertrandt A et al., J Clin Oncol 2011 May 31;: Barron TI et al., J Clin Oncol 2011 May 31;:
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Earlier Is Better: Preop β-Blockers in Vascular Surgery Patients
- March 7, 2011
- Grace C. Huang, MD
- Hospital Medicine
Initiation of preoperative β-blockers >1 week before vascular surgery was associated with better outcomes.- Reviewing:
- Flu W-J et al., J Am Coll Cardiol 2010 Nov 30; 56:1922.
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Response to β-Blocker Therapy and Risk for Variceal Bleeding
- September 4, 2009
- Atif Zaman, MD, MPH
- Gastroenterology
Hemodynamic reduction of >10% from baseline reduces long-term risk for first variceal hemorrhage and ascites.- Reviewing:
- Villanueva C et al., Gastroenterology 2009 Jul; 137:119.
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Lower Heart Rate, Not Higher β-Blocker Dose, Leads to Better Survival in Heart Failure Patients
Risk for death was 18% lower for every 5 bpm reduction with β-blocker treatment.- Reviewing:
- McAlister FA et al., Ann Intern Med 2009 Jun 2; 150:784.
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Beta-Blockers Highly Effective in Long-QT Syndrome Type 1
- January 28, 2009
- Mark S. Link, MD
- Cardiology
In an analysis of registry data, most clinical failures of beta-blocker treatment resulted from noncompliance or coadministration of QT-prolonging drugs.- Reviewing:
- Vincent GM et al., Circulation 2009 Jan 20; 119:215.
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Which Beta-Blocker is Best for Patients with Heart Failure?
- December 17, 2008
- Joel M. Gore, MD
- Cardiology
Evidence of efficacy might not be the most important factor to consider.- Reviewing:
- Kramer JM et al., Arch Intern Med 2008 Dec 8; 168:2422. Go AS et al., Arch Intern Med 2008 Dec 8; 168:2415.
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Beta-Blockers Should Not Be First in Line for Treating Hypertension
- December 10, 2008
- Mark S. Link, MD
- Cardiology
In a meta-analysis, lowering of heart rate was associated with increases in cardiac mortality, risk for nonfatal MI, and heart failure.- Reviewing:
- Bangalore S et al., J Am Coll Cardiol 2008 Oct 28; 52:1482. Kaplan NM., J Am Coll Cardiol 2008 Oct 28; 52:1490.
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β-Blockers to Prevent Heart Failure in Hypertensive Patients?
- November 26, 2008
- Kirsten E. Fleischmann, MD, MPH
- General Medicine
β-blockers were similar to other agents for preventing HF but conferred risk for stroke in older patients.- Reviewing:
- Bangalore S et al., J Am Coll Cardiol 2008 Sep 23; 52:1062. Fowler MB., J Am Coll Cardiol 2008 Sep 23; 52:1073.
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Another Look at Perioperative Beta-Blockers in Noncardiac Surgery
- November 12, 2008
- Beat J. Meyer, MD
- Cardiology
In a meta-analysis, a beneficial therapy is challenged by debatable evidence.- Reviewing:
- Bangalore S et al., Lancet 2008 Nov 11;: Boersma E and Poldermans D., Lancet 2008 Nov 11;:
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EBL vs. β-Blockers for Preventing Variceal Hemorrhage Free
- November 30, 2007
- Atif Zaman, MD, MPH
- Gastroenterology
In an updated meta-analysis, endoscopic band ligation was superior to β-blocker therapy in preventing first bleeds.- Reviewing:
- Tripathi D et al., Eur J Gastroenterol Hepatol 2007 Oct; 19:835.
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Beta-Blockers and Coronary Atherosclerosis Progression
- August 1, 2007
- Joel M. Gore, MD
- Cardiology
A pooled analysis of four intravascular ultrasonography trials suggests a benefit in patients with established coronary artery disease.- Reviewing:
- Sipahi I et al., Ann Intern Med 2007 Jul 3; 147:10-8.
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Beta-Blockers in Acute Ischemic Stroke
- June 26, 2007
- Karen L. Furie, MD
- Neurology
In this exploratory study, researchers examined potential benefits of beta-blockers in acute ischemic stroke.- Reviewing:
- Laowattana S and Oppenheimer SM., Neurology 2007 Feb 13; 68:509-14.
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β-Blockers for Patients Undergoing Noncardiac Surgery — The Saga Continues
- November 29, 2006
- Allan S. Brett, MD
- General Medicine
Two randomized trials call into question the recommendation of perioperative beta-blockade in patients undergoing noncardiac surgery.- Reviewing:
- Juul AB et al., BMJ 2006 Jun 24; 332:1482-5. Yang H et al., Am Heart J 2006 Nov; 152:983-90. McCullough PA., Am Heart J 2006 Nov; 152:815-8.
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Another Look at β-Blockers for Hypertension
- June 23, 2006
- Allan S. Brett, MD
- General Medicine
β-blockers might be more acceptable first-line drugs for younger hypertensive patients than for older patients.- Reviewing:
- Khan N and McAlister FA., CMAJ 2006 Jun 6; 174:1737-42.
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Perioperative Beta-Blocker Therapy for Noncardiac Surgery
- May 18, 2006
- Hugh Calkins, MD
- Cardiology
A focused guideline update from the American College of Cardiology and American Heart Association- Reviewing:
- Fleisher LA et al.,;:
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