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Search for beta-blockers in all Journal Watch editions
Physician-authored summaries on the latest research on beta-blockers, editorials on beta-blockers, and perspectives on beta-blockers - drawn from the top medical journals.
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You searched for: beta-blockers
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Beta-Blockers as Breast Cancer Therapy?
- June 28, 2011
- William J. Gradishar, MD
- Oncology and Hematology
Two studies suggest beneficial effects on breast cancer recurrence and survival, but many questions remain.- Reviewing:
- Melhem-Bertrandt A et al., J Clin Oncol 2011 May 31;: Barron TI et al., J Clin Oncol 2011 May 31;:
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Earlier Is Better: Preop β-Blockers in Vascular Surgery Patients
- March 7, 2011
- Grace C. Huang, MD
- Hospital Medicine
Initiation of preoperative β-blockers >1 week before vascular surgery was associated with better outcomes.- Reviewing:
- Flu W-J et al., J Am Coll Cardiol 2010 Nov 30; 56:1922.
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Response to β-Blocker Therapy and Risk for Variceal Bleeding
- September 4, 2009
- Atif Zaman, MD, MPH
- Gastroenterology
Hemodynamic reduction of >10% from baseline reduces long-term risk for first variceal hemorrhage and ascites.- Reviewing:
- Villanueva C et al., Gastroenterology 2009 Jul; 137:119.
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Lower Heart Rate, Not Higher β-Blocker Dose, Leads to Better Survival in Heart Failure Patients
Risk for death was 18% lower for every 5 bpm reduction with β-blocker treatment.- Reviewing:
- McAlister FA et al., Ann Intern Med 2009 Jun 2; 150:784.
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Beta-Blockers Highly Effective in Long-QT Syndrome Type 1
- January 28, 2009
- Mark S. Link, MD
- Cardiology
In an analysis of registry data, most clinical failures of beta-blocker treatment resulted from noncompliance or coadministration of QT-prolonging drugs.
CME Exam- Reviewing:
- Vincent GM et al., Circulation 2009 Jan 20; 119:215.
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Which Beta-Blocker is Best for Patients with Heart Failure?
- December 17, 2008
- Joel M. Gore, MD
- Cardiology
Evidence of efficacy might not be the most important factor to consider.
CME Exam- Reviewing:
- Kramer JM et al., Arch Intern Med 2008 Dec 8; 168:2422. Go AS et al., Arch Intern Med 2008 Dec 8; 168:2415.
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Beta-Blockers Should Not Be First in Line for Treating Hypertension
- December 10, 2008
- Mark S. Link, MD
- Cardiology
In a meta-analysis, lowering of heart rate was associated with increases in cardiac mortality, risk for nonfatal MI, and heart failure.
CME Exam- Reviewing:
- Bangalore S et al., J Am Coll Cardiol 2008 Oct 28; 52:1482. Kaplan NM., J Am Coll Cardiol 2008 Oct 28; 52:1490.
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β-Blockers to Prevent Heart Failure in Hypertensive Patients?
- November 26, 2008
- Kirsten E. Fleischmann, MD, MPH
- General Medicine
β-blockers were similar to other agents for preventing HF but conferred risk for stroke in older patients.
CME Exam- Reviewing:
- Bangalore S et al., J Am Coll Cardiol 2008 Sep 23; 52:1062. Fowler MB., J Am Coll Cardiol 2008 Sep 23; 52:1073.
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Another Look at Perioperative Beta-Blockers in Noncardiac Surgery
- November 12, 2008
- Beat J. Meyer, MD
- Cardiology
In a meta-analysis, a beneficial therapy is challenged by debatable evidence.- Reviewing:
- Bangalore S et al., Lancet 2008 Nov 11;: Boersma E and Poldermans D., Lancet 2008 Nov 11;:
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EBL vs. β-Blockers for Preventing Variceal Hemorrhage Free
- November 30, 2007
- Atif Zaman, MD, MPH
- Gastroenterology
In an updated meta-analysis, endoscopic band ligation was superior to β-blocker therapy in preventing first bleeds.- Reviewing:
- Tripathi D et al., Eur J Gastroenterol Hepatol 2007 Oct; 19:835.
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Beta-Blockers and Coronary Atherosclerosis Progression
- August 1, 2007
- Joel M. Gore, MD
- Cardiology
A pooled analysis of four intravascular ultrasonography trials suggests a benefit in patients with established coronary artery disease.
CME Exam- Reviewing:
- Sipahi I et al., Ann Intern Med 2007 Jul 3; 147:10-8.
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Beta-Blockers in Acute Ischemic Stroke
- June 26, 2007
- Karen L. Furie, MD
- Neurology
In this exploratory study, researchers examined potential benefits of beta-blockers in acute ischemic stroke.- Reviewing:
- Laowattana S and Oppenheimer SM., Neurology 2007 Feb 13; 68:509-14.
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β-Blockers for Patients Undergoing Noncardiac Surgery — The Saga Continues
- November 29, 2006
- Allan S. Brett, MD
- General Medicine
Two randomized trials call into question the recommendation of perioperative beta-blockade in patients undergoing noncardiac surgery.- Reviewing:
- Juul AB et al., BMJ 2006 Jun 24; 332:1482-5. Yang H et al., Am Heart J 2006 Nov; 152:983-90. McCullough PA., Am Heart J 2006 Nov; 152:815-8.
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Another Look at β-Blockers for Hypertension
- June 23, 2006
- Allan S. Brett, MD
- General Medicine
β-blockers might be more acceptable first-line drugs for younger hypertensive patients than for older patients.- Reviewing:
- Khan N and McAlister FA., CMAJ 2006 Jun 6; 174:1737-42.
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Perioperative Beta-Blocker Therapy for Noncardiac Surgery
- May 18, 2006
- Hugh Calkins, MD
- Cardiology
A focused guideline update from the American College of Cardiology and American Heart Association- Reviewing:
- Fleisher LA et al.,;:
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Statins and β-Blockers Can Favorably Alter Initial CHD Presentation
- March 14, 2006
- Richard Saitz, MD, MPH, FACP, FASAM
- General Medicine
Patients who took statins and β-blockers were more likely to present with angina than MI.- Reviewing:
- Go AS et al., Ann Intern Med 2006 Feb 21; 144:229-38.
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Do Beta-Blockers Add Benefit to Spironolactone in Severe HF?
- February 16, 2006
- Frederick A. Masoudi, MD, MSPH
- Cardiology
Carvedilol improved outcomes, regardless of baseline spironolactone use, in the COPERNICUS trial.- Reviewing:
- Krum H et al. for the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) Study Group., Am Heart J 2006 Jan; 151:55-61.
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Nonselective β-Blockers Don’t Prevent Varices in Cirrhotic Patients
- January 17, 2006
- Atif Zaman, MD, MPH
- Gastroenterology
β-blockers should be given only to cirrhotic patients with existing varices.- Reviewing:
- Groszmann RJ et al., N Engl J Med 2005 Nov 24; 353:2254-61.
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Can β-Blockers Prevent Gastroesophageal Varices?
- December 9, 2005
- Allan S. Brett, MD
- General Medicine
Although nonselective beta-blockers reduce the incidence of bleeding in patients with cirrhosis who already have varices, they failed to prevent varices from developing in this randomized trial.- Reviewing:
- Groszmann RJ et al., N Engl J Med 2005 Nov 24; 353:2254-61.
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Rethinking the Role of Beta-Blockers in Hypertension
- November 25, 2005
- Beat J. Meyer, MD
- Cardiology
In primary hypertension, beta-blockers appear to offer no advantage for preventing MI or death and less advantage than other antihypertensives for preventing stroke.- Reviewing:
- Lindholm LH et al., Lancet 2005 Oct 29; 366:1545-53. Beevers DG., Lancet 2005 Oct 29; 366:1510-2.
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