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Search for basal cell carcinoma in all Journal Watch editions
Physician-authored summaries on the latest research on basal cell carcinoma, editorials on basal cell carcinoma, and perspectives on basal cell carcinoma - drawn from the top medical journals.
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You searched for: basal cell carcinoma
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Tanning Increases BCC in Young Adults — More Evidence
- November 16, 2012
- Murad Alam, MD, MSCI
- Dermatology
Indoor tanners are much more likely than others to develop basal cell carcinoma before age 40; the risk is pronounced in young women.- Reviewing:
- Ferrucci LM et al., J Am Acad Dermatol 2012 Oct; 67:552.
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Nevi Are a Risk Factor for Basal Cell Carcinoma Free
- October 19, 2012
- Craig A. Elmets, MD
- Dermatology
Patients with multiple nevi have probably had considerable sun or tanning bed exposure and should be examined for BCC.- Reviewing:
- Richmond-Sinclair NM et al., J Eur Acad Dermatol Venereol 2012 Sep; 26:1092.
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PDT for Basal Cell Carcinoma: A Long-Term Follow-Up Free
- June 15, 2012
- Craig A. Elmets, MD
- Dermatology
Long-term results show 5-aminolevulinic acid photodynamic therapy to be beneficial for basal cell carcinomas when surgery is not a good option.- Reviewing:
- Christensen E et al., Br J Dermatol 2012 Jun; 166:1342.
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Medical Management of Basal Cell Carcinoma with a Small-Molecule Hedgehog Inhibitor
- June 6, 2012
- Craig A. Elmets, MD
- Dermatology
Two recent studies show efficacy of vismodegib for treating locally advanced or metastatic BCCs.- Reviewing:
- Sekulic A et al., N Engl J Med 2012 Jun 7; 366:2171. Tang JY et al., N Engl J Med 2012 Jun 7; 366:2180.
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Basal Cell Carcinomas of the Ear Are More Aggressive Than Those Sited Elsewhere
- May 25, 2012
- Murad Alam, MD, MSCI
- Dermatology
An aggressive phenotype was found in 57% of ear BCCs versus 38% of cheek BCCs.- Reviewing:
- Jarell AD and Mully TW., J Am Acad Dermatol 2012 May; 66:780.
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Basal Cell Carcinoma at a Young Age: Another Consequence of Tanning Beds Free
- February 3, 2012
- Craig A. Elmets, MD
- Dermatology
Tanning bed users younger than 40 developed early-onset BCCs significantly more often than nonusers.- Reviewing:
- Ferrucci LM et al., J Am Acad Dermatol 2011 Dec 8;:
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Dissecting BCC Risk Free
- August 21, 2009
- Hensin Tsao, MD, PhD
- Dermatology
Some genetic components of the risk for basal cell carcinoma have nothing to do with pigmentation.- Reviewing:
- Stacey SN et al., Nat Genet 2009 Aug; 41:909.
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Photodynamic Therapy and the Immune System
- August 14, 2009
- Craig A. Elmets, MD
- Dermatology
PDT apparently increases antitumor immunity in addition to directly destroying lesions of basal cell carcinoma.- Reviewing:
- Kabingu E et al., Clin Cancer Res 2009 Jul 1; 15:4460.
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Specific Genetic Risk Factors for Basal Cell Carcinoma
- November 7, 2008
- Hensin Tsao, MD, PhD
- Dermatology
Some genetic factors were specific risks for BCC and not for cutaneous melanoma or squamous cell carcinoma.- Reviewing:
- Stacey SN et al., Nat Genet 2008 Nov; 40:1313.
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Geographic Variation and Skin Cancer
- March 14, 2008
- George J. Hruza, MD
- Dermatology
Residence in sunny or high-altitude locales increased risks for basal cell and squamous cell carcinomas in a large cohort.- Reviewing:
- Qureshi AA et al., Arch Intern Med 2008 Mar 10; 168:501.
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Superficial BCC and Imiquimod: The European Experience
- June 28, 2005
- George J. Hruza, MD
- Dermatology
Imiquimod has been approved in the U.S. for the treatment of nonfacial, superficial basal cell carcinoma (sBCC), with published tumor clearance rates of approximately 80%. . . .- Reviewing:
- Schulze HJ et al., Br J Dermatol 2005 May; 152:939-47.
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Photodynamic Therapy for Basal Cell Nevus Syndrome
- February 15, 2005
- George J. Hruza, MD
- Dermatology
Aminolevulinic acid photodynamic therapy (ALA-PDT) with blue or yellow light is used to treat acne, photodamage, actinic keratoses, and excess hair. More deeply penetrating red . . .- Reviewing:
- Oseroff AR et al., Arch Dermatol 2005 Jan; 141:60-7.
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Mohs Surgery vs. Excision for Basal Cell Carcinoma
- December 14, 2004
- George J. Hruza, MD
- Dermatology
Mohs micrographic surgery (MMS) has a long track record of achieving the highest cure rate and the best tissue conservation for basal cell carcinoma (BCC). . . .- Reviewing:
- Smeets NWJ et al., Lancet 2004 Nov 13; 364:1766-72.
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Which Treatment for Basal Cell Carcinoma?
- October 26, 2004
- Keith I. Marton, MD
- General Medicine
Given the limited research comparing treatments for basal cell carcinoma of the skin, the most common human cancer, researchers undertook a systematic review of randomized . . .- Reviewing:
- Bath-Hextall F et al., BMJ 2004 Sep 25; 329:705-8.
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Imiquimod for Basal Cell Carcinoma: Act II
- October 15, 2002
- George J. Hruza, MD
- Dermatology
Topical 5% imiquimod cream has been shown to achieve histologic tumor clearance rates of about 85% in the treatment of superficial basal cell carcinoma (BCC). . . .- Reviewing:
- Shumack S et al., Arch Dermatol 2002 Sep; 138:1165-71.
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Imiquimod for Superficial Basal Cell Carcinoma
- May 14, 2001
- GJ Hruza
- Dermatology
Imiquimod is an immune-response modifier that induces cytokines, including interferon-α, interleukin 12, and interferon-γ; it has shown some efficacy in the treatment of basal cell . . .- Reviewing:
- Marks R et al., J Am Acad Dermatol 2001 May; 44:
807 813 .
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Risk of Basal Cell Carcinoma from PUVA in Childhood
- February 1, 1997
- K Wiss
- Dermatology
Oral methoxsalen photochemotherapy is an effective treatment for psoriasis in adults. It is well established that PUVA increases the risk of squamous cell carcinoma in . . .- Reviewing:
- Stern RS et al., J Pediatr 1996; 129:
915 917 .
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Role of p53 in Pathogenesis of Basal Cell Carcinoma
- August 1, 1995
- BR Smoller
- Dermatology
The tumor-suppressor gene p53 has been reported to be overexpressed in cutaneous and internal malignancies. It is not known whether this genetic mutation is an . . .- Reviewing:
- Urano Y et al., J Invest Dermatol 1995; 104:
928 932 .
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Chasing the Hedgehog: aPKC as a Potential Target in BCC
- March 15, 2013
- Kenneth Y. Tsai, MD, PhD
- Dermatology
By regulating GLI activation, atypical protein kinase C ι/λ regulated growth of basal cell carcinomas.- Reviewing:
- Atwood SX et al., Nature 2013 Feb 28; 494:484.
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Superficial X-Ray in the Treatment of Basal and Squamous Cell Carcinomas
- February 15, 2013
- Murad Alam, MD, MSCI
- Dermatology
For very elderly or debilitated patients who have very large skin cancers and are unable to tolerate surgery, radiation remains a reasonable option.- Reviewing:
- Cognetta AB et al., J Am Acad Dermatol 2012 Dec; 67:1235.
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