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Search for antihypertensives in all Journal Watch editions
Physician-authored summaries on the latest research on antihypertensives, editorials on antihypertensives, and perspectives on antihypertensives - drawn from the top medical journals.
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You searched for: antihypertensives
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Follow-Up: An Interview on Antihypertensive Agents and Cancer Risk Free
- December 6, 2010
- Physician's First Watch
Clinical Conversations has an interview with Sripal Bangalore, the first author of a Lancet Oncology meta-analysis that we covered last week. The analysis found... -
Meta-Analysis Examines Association of Antihypertensives and Diabetes Free
- January 19, 2007
- Physician's First Watch
Researchers in today's Lancet rank antihypertensive drug classes in order of their association with incident diabetes using a fairly new meta-analytic technique that allows... -
ACE Inhibitors and ARBs vs. Other Antihypertensives for Renoprotection
- January 27, 2006
- Bruce Soloway, MD
- General Medicine
Do different classes of antihypertensives have specific protective effects, or do all of them improve outcomes primarily by reducing blood pressure?- Reviewing:
- Casas JP et al., Lancet 2005 Dec 10; 366:2026-33.
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Newer vs. Older Antihypertensives: New Data, Same Controversy
- October 21, 2005
- Bruce Soloway, MD
- General Medicine
Treatment of hypertension reduces risk for adverse cardiovascular events, but whether this effect varies among different classes of antihypertensive drugs when blood pressure is comparably . . .- Reviewing:
- Dahlöf B et al., Lancet 2005 Sep 10; 366:895-906. Poulter NR et al., Lancet 2005 Sep 10; 366:907-13. Staessen JA and Birkenhäger WH., Lancet 2005 Sep 10; 366:869-71.
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Choice of Antihypertensive Agents for Patients with Metabolic Syndrome: ALLHAT Results
- March 11, 2008
- Jamaluddin Moloo, MD, MPH
- General Medicine
Diuretics should continue to be first-line agents for treating patients with hypertension.
Audio Interview- Reviewing:
- Black HR et al., Diabetes Care 2008 Feb; 31:353.
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Renal Outcomes Data Challenge ACE Inhibitors, ARBs as First-Line Antihypertensives
- February 2, 2006
- Frederick A. Masoudi, MD, MSPH
- Cardiology
A large meta-analysis revealed little renal benefit beyond BP lowering.- Reviewing:
- Casas JP et al., Lancet 2005 Dec 10; 366:2026-33.
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Similar Renal Outcomes with Different Antihypertensives
- June 24, 2005
- JoAnne M. Foody, MD
- Cardiology
Hypertension is the most common comorbid condition in patients with end-stage renal disease (ESRD). Several studies have shown that adequate antihypertensive treatment can help to . . .- Reviewing:
- Rahman M et al. for the ALLHAT Collaborative Research Group., Arch Intern Med 2005 Apr 25; 165:936-46.
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Are Antihypertensive Drugs Neuroprotective in Parkinson Disease?
- April 15, 2008
- Robert L. Rodnitzky, MD
- Neurology
A large case-control study suggests that calcium channel blockers are the only antihypertensives that reduce the risk for Parkinson disease.- Reviewing:
- Becker C et al., Neurology 2008 Feb 6;:
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Hypertension Drug Combo plus NSAIDs Associated with Risk for Acute Kidney Injury Free
- January 9, 2013
- Physician's First Watch
Common antihypertensive agents are associated with increased risk for kidney injury when used concurrently with NSAIDs, according to a BMJ article.Using U.K. national databases... -
Hypertension Associated with Psoriasis Is Difficult to Treat
- April 29, 2011
- Jeffrey P. Callen, MD
- Dermatology
The mechanism behind this association remains unknown.- Reviewing:
- Armstrong AW et al., PLoS ONE 2011 Mar; 6:e18227.
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ARBs plus ACE Inhibitors, Used in Combination, Seem to Heighten Cancer Risk Free
- November 30, 2010
- Physician's First Watch
Patients taking angiotensin-receptor blockers along with angiotensin-converting–enzyme inhibitors — but not ARBs alone — have a modestly increased risk for cancer, according to a... -
Price of Nonadherence to Antihypertensive Medications
- November 10, 2009
- Kirsten E. Fleischmann, MD, MPH
- General Medicine
High adherers had a significantly lower risk for cardiovascular disease.- Reviewing:
- Mazzaglia G et al., Circulation 2009 Oct 20; 120:1598. Chobanian AV., Circulation 2009 Oct 20; 120:1558.
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Intensive Blood Pressure Control Slows Progression of Chronic Kidney Disease in Children Free
- October 21, 2009
- F. Bruder Stapleton, MD
- Pediatrics and Adolescent Medicine
The renoprotective effect of blood pressure control is independent of ACE inhibition.- Reviewing:
- The ESCAPE Trial Group., N Engl J Med 2009 Oct 22; 361:1639. Ingelfinger JR., N Engl J Med 2009 Oct 22; 361:1701.
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The Hypertension–Dementia Connection: A Chance to Make a Difference?
- August 25, 2009
- David A. Drachman, MD
- Neurology
What is the effect of treating hypertension on the incidence of dementia or the development of Alzheimer pathology?- Reviewing:
- Hoffman LB et al., Neurology 2009 May 19; 72:1720. Haag MDM et al., Neurology 2009 May 19; 72:1727.
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Antihypertensive Effective Against Alzheimer Disease in Mouse Model Free
- October 29, 2007
- Physician's First Watch
Your patients might be asking about research showing that the angiotensin-receptor blocker valsartan may help prevent or slow the progression of Alzheimer disease (AD... -
Under Pressure?
- August 28, 2007
- Bert B. Vargas, MD, and David W. Dodick, MD
- Neurology
Ruling out essential hypertension as a secondary cause of hypnic headaches- Reviewing:
- Gil-Gouveia R and Goadsby PJ., J Neurol 2007 May; 254:646-54.
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Lowering Blood Pressure Improves Diastolic Function Irrespective of Drug Type
- July 11, 2007
- Beat J. Meyer, MD
- Cardiology
An ARB demonstrated no significant advantage over other drug classes in patients with diastolic dysfunction but without LV hypertrophy.- Reviewing:
- Solomon SD et al., Lancet 2007 Jun 23; 369:2079-87. Ahmed A et al., Lancet 2007 Jun 23; 369:2053-4.
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Diabetes Risk with Antihypertensive Meds Free
- February 7, 2007
- Harlan M. Krumholz, MD, SM
- Cardiology
A meta-analysis yields a ranking of antihypertensive drug classes according to their association with incident diabetes.- Reviewing:
- Elliott WJ and Meyer PM., Lancet 2007 Jan 20; 369:201-7.
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ACE Inhibitors May Prevent Rupture of Abdominal Aortic Aneurysms
- September 26, 2006
- Bruce Soloway, MD
- General Medicine
A review of data on hospitalized patients revealed that ACE inhibitors, but not other antihypertensives, were associated with lower risk for rupture.- Reviewing:
- Hackam DG et al., Lancet 2006 Aug 19; 368:659-65.
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ACE Inhibitors Are Teratogenic in the First Trimester Free
- July 5, 2006
- Harlan M. Krumholz, MD, SM
- Cardiology
Specifically, these drugs were associated with increased infant risks for cardiovascular and nervous system anomalies.- Reviewing:
- Cooper WO et al., N Engl J Med 2006 Jun 8; 354:2443-51. Friedman JM., N Engl J Med 2006 Jun 8; 354:2498-500.
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