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Search for antihistamine in all Journal Watch editions
Physician-authored summaries on the latest research on antihistamine, editorials on antihistamine, and perspectives on antihistamine - drawn from the top medical journals.
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You searched for: antihistamine
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Combination Nasal Steroid–Antihistamine Is More Effective Than Either Agent Alone
- June 19, 2012
- David J. Amrol, MD
- General Medicine
For patients with allergic rhinitis, twice-daily azelastine plus fluticasone cut nasal symptoms.- Reviewing:
- Carr W et al., J Allergy Clin Immunol 2012 May; 129:1282.
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Antihistamine Fails to Prevent Nevirapine Rash
- August 1, 2004
- Abigail Zuger, MD
- HIV/AIDS
In the first randomized controlled trial of antihistamines for prevention of cutaneous nevirapine reactions, the results are negative.- Reviewing:
- Launay O et al., Clin Infect Dis 2004 Apr 15; 38:e66-72.
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Whealy Doses Free
- April 16, 2010
- Mark V. Dahl, MD
- Dermatology
High doses of antihistamines alleviated urticarial wheals better than the standard dose.- Reviewing:
- Staevska M et al., J Allergy Clin Immunol 2010 Mar; 125:676.
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New Possibilities for Treating Alzheimer Disease?
- September 8, 2008
- Jonathan Silver, MD
- Psychiatry
An old medication may help; immunization doesn’t; and exercise may be good — but just for general health.- Reviewing:
- Doody RS et al., Lancet 2008 Jul 19; 372:207. Holmes C et al., Lancet 2008 Jul 19; 372:216. Burns JM et al., Neurology 2008 Jul 15; 71:210.
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Old Antihistamine Could Improve Symptoms in Alzheimer Patients
- July 31, 2008
- Bruce Soloway, MD
- General Medicine
After 1 year of treatment, Alzheimer patients still benefited from dimebon.- Reviewing:
- Doody RS et al., Lancet 2008 Jul 19; 372:207.
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Allergic Rhinitis Can Drag Test Scores Down
- August 23, 2007
- Robert A. Dershewitz, MD, MSc
- General Medicine
Symptomatic allergic rhinitis can adversely affect test scores, and sedating antihistamines may compound the learning impairment.- Reviewing:
- Walker S et al., J Allergy Clin Immunol 2007 Aug; 120:381-7.
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A First-Generation Antihistamine Helps the Common Cold
- December 1, 1997
- A Zuger
- Dermatology
Although antihistamines are included in many over-the-counter cold remedies, until now formal studies have failed to prove their efficacy. This large, multicenter, blinded study carefully . . .- Reviewing:
- Turner RB et al., Clin Infect Dis 1997 Oct; 25:
824 830 .
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A FIRST-GENERATION ANTIHISTAMINE HELPS THE COMMON COLD.
- October 28, 1997
- A Zuger
- General Medicine
Although antihistamines are included in many over-the- counter cold remedies, until now formal studies have failed to prove their efficacy. This large, multicenter, blinded study . . .- Reviewing:
- Turner RB et al., Clin Infect Dis 1997 Oct; 25:
824 830 .
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STEROID NASAL SPRAY OR ANTIHISTAMINE FOR ALLERGIC RHINITIS?
- May 17, 1996
- AS Brett
- General Medicine
A previous study, performed during the winter months in Texas, demonstrated that the steroid nasal spray fluticasone propionate was superior to the second-generation antihistamine terfenadine . . .- Reviewing:
- Bronsky EA et al., J Allergy Clin Immunol 1996 Apr; 97:
915 921 .
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ANTIHISTAMINE-DECONGESTANT COMBINATIONS DON'T HELP.
- February 8, 1991
- DMB
- General Medicine
Simple, commonplace treatments too often escape controlled clinical trials. This one did not. Researchers at Johns Hopkins conducted a randomized, placebo-controlled trial of a popular . . .- Reviewing:
- Hutton N et al., J Pediatr 1991 Jan; 118:
125 130 .
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PPI vs. H2-Blocker to Prevent GI Bleeding Caused by Dual Antiplatelet Therapy
- April 3, 2012
- Allan S. Brett, MD
- General Medicine
During several months of treatment for acute coronary syndrome, esomeprazole was more effective than famotidine.- Reviewing:
- Ng F-H et al., Am J Gastroenterol 2012 Mar; 107:389.
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PPIs Are the Most Effective Drugs to Reduce Risk for Upper GI Bleeding
Proton-pump inhibitors bested histamine-2–receptor antagonists and nitrates in patients taking gastrotoxic drugs and in the general population.
CME Exam- Reviewing:
- Lin KJ et al., Gastroenterology 2011 Jul; 141:71.
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Most Inpatients Do Not Require Acid Suppression
Although effective, such drugs are needed only for critically ill patients at risk for upper GI bleeding.- Reviewing:
- Herzig SJ et al., Arch Intern Med 2011 Jun 13; 171:991.
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FDA Pulling Unapproved Prescription Cough, Cold, and Allergy Drugs Free
- March 3, 2011
- Physician's First Watch
The FDA is removing roughly 500 prescription cough, cold, and allergy medications from the market because they have not gone through the proper approval process... -
PPIs and H2-Blockers: Not So Benign
- February 14, 2011
- Daniel D. Dressler, MD, MSc, SFHM
- Hospital Medicine
Acid suppression with proton-pump inhibitors or histamine-2 blockers heightens risk for pneumonia in hospitalized patients.- Reviewing:
- Eom C-S et al., CMAJ 2010 Dec 20;:
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Is Acid-Reduction Therapy Associated with Risk for Hip Fractures?
Another study adds to the confusion about this potential link.
CME Exam- Reviewing:
- Corley DA et al., Gastroenterology 2010 Jul; 139:93.
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Tylenol, Benadryl Recall Expanded Free
- June 16, 2010
- Physician's First Watch
McNeil Consumer Healthcare has expanded its January 15 recall to include four lots of Benadryl Allergy Ultratab Tablets (100 count) and one lot of Extra... -
Proton-Pump Inhibitor Dosing and Negative Consequences
- June 8, 2010
- Jamaluddin Moloo, MD, MPH
- General Medicine
Four studies about the effects of PPI therapy- Reviewing:
- Wang C-H et al., Arch Intern Med 2010 May 10; 170:751. Gray SL et al., Arch Intern Med 2010 May 10; 170:765. Linsky A et al., Arch Intern Med 2010 May 10; 170:772. Howell MD et al., Arch Intern Med 2010 May 10; 170:784. Katz MH., Arch Intern Med 2010 May 10; 170:747.
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Metoclopramide vs. Promethazine for Hyperemesis Gravidarum
- May 27, 2010
- Wendy S. Biggs, MD
- Women's Health
Both agents were effective, but promethazine had more adverse effects — and has a black box warning.- Reviewing:
- Tan PC et al., Obstet Gynecol 2010 May; 115:975.
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Proton-Pump Inhibitors Increase Risks for C. difficile Infection Free
- May 11, 2010
- Physician's First Watch
Proton-pump inhibitors (PPIs) are overprescribed, and as currently used, their harms mostly outweigh their benefits, researchers and an editorialist argue in the Archives of...
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