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Search for adenovirus in all Journal Watch editions
Physician-authored summaries on the latest research on adenovirus, editorials on adenovirus, and perspectives on adenovirus - drawn from the top medical journals.
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A Novel Adenovirus with Cross-Species Transmission
- July 27, 2011
- Thomas Glück, MD
- Infectious Diseases
A newly identified adenovirus responsible for a deadly outbreak among monkeys was transmitted to a researcher — and to the researcher's family.- Reviewing:
- Chen EC et al., PLoS Pathog 2011 Jul 14; 7:e1002155.
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Obesity and Adenovirus
- October 13, 2010
- Howard Bauchner, MD
- Pediatrics and Adolescent Medicine
Data support an association between adenovirus and obesity in children but do not prove causality.- Reviewing:
- Gabbert C et al., Pediatrics 2010 Oct; 126:721.
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Adenovirus 14 Associated with Severe Pneumonia
- February 20, 2008
- Neil M. Ampel, MD
- Infectious Diseases
In New Mexico, three cases of severe acute respiratory tract infection — one resulting in death — were associated with adenovirus 14.- Reviewing:
- Louie JK et al., Clin Infect Dis 2008 Feb 1; 46:421.
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New, More Virulent, Adenovirus Strain Reported in Clusters
- January 9, 2008
- Peggy Sue Weintrub, MD
- Pediatrics and Adolescent Medicine
Consider adenovirus in cases of severe pneumonia and prolonged respiratory tract infection.- Reviewing:
- Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2007 Nov 16; 56:1181.
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Adenovirus Linked to Childhood Obesity Free
- September 20, 2010
- Physician's First Watch
Parents may ask about a Pediatrics study showing an association in children between obesity and antibodies to adenovirus-36, previously associated with obesity in adults... -
New Adenovirus Variant Causing Severe Disease Free
- November 16, 2007
- Physician's First Watch
The CDC reports that a new adenovirus variant has caused at least 140 cases of severe respiratory illness in the United States, including 10 deaths... -
A Cold That Kills?
- February 15, 2008
- Diane M. Birnbaumer, MD, FACEP
- Emergency Medicine
Cases of severe respiratory disease caused by adenovirus serotype 14 raise concern.- Reviewing:
- Louie JK et al., Clin Infect Dis 2008 Feb 1; 46:421.
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Managing Viral Infections After Stem Cell Transplantation
- April 30, 2013
- David Green, MD, PhD
- Oncology and Hematology
Nearly three fourths of transplant patients with refractory infections responded to treatment with banked, virus-specific T-cells.- Reviewing:
- Leen AM et al., Blood 2013 Apr 22;:
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FDA Approves Rapid Test for 12 Different Respiratory Viral Infections Free
- January 7, 2008
- Physician's First Watch
The FDA has approved a nucleic acid test that simultaneously checks for 12 different respiratory viruses. The test, conducted on throat secretions, is called the... -
Nongonococcal Urethritis — From a Virus?
- March 10, 2006
- Daniel J. Diekema, MD, MS
- Infectious Diseases
Adenoviruses and HSV-1 may be important causes of nongonococcal urethritis associated with insertive oral sex.- Reviewing:
- Bradshaw CS et al., J Infect Dis 2006 Feb 1; 193:336-45.
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Gene Therapy for Christmas Disease
- January 10, 2012
- David Green, MD, PhD
- Oncology and Hematology
A single infusion of a liver-targeted adenovirus vector expressing the human factor IX transgene produces a sustained increase in factor IX levels with few adverse effects.- Reviewing:
- Nathwani AC et al., N Engl J Med 2011 Dec 22; 365:2357. Ponder KP., N Engl J Med 2011 Dec 22; 365:2424.
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Improving Heart Function in Viral Cardiomyopathy
- December 23, 2009
- Neil M. Ampel, MD
- Infectious Diseases
In a murine model, gene therapy resulted in improved myocardial function when administered before or concomitantly with coxsackievirus infection.- Reviewing:
- Pinkert S et al., Circulation 2009 Dec 8; 120:2358.
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Severe Respiratory Infection Caused by Human Ad14
- April 29, 2009
- Larry M. Baddour, MD
- Infectious Diseases
In two geographically separate outbreaks of respiratory infections, illness caused by human adenovirus serotype 14 ranged from mild to severe.- Reviewing:
- Lewis PF et al., J Infect Dis 2009 May 15; 199:1427. Tate JE et al., J Infect Dis 2009 May 15; 199:1419. Gray GC and Chorazy ML., J Infect Dis 2009 May 15; 199:1413.
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Adenovirus Infections Skyrocket After Vaccine Production Stops
- November 16, 2000
- B Britigan
- Infectious Diseases
Before 1971, respiratory infections with adenovirus were epidemic among new U.S. military recruits, leading to hospitalization in up to 20 percent of cases. Introduction and . . .- Reviewing:
- Gray GC et al., Clin Infect Dis 2000 Sep; 31:
663 670 . Katz SL., Clin Infect Dis 2000 Sep; 31:671 672 .
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Adenovirus Respiratory Disease Rebounds in Vaccine's Absence
- February 1, 2000
- N Blacklow
- Infectious Diseases
Because successful vaccination programs are not normally discontinued, opportunities to test their clinical impact rarely arise. Such an opportunity developed in 1996, when the only . . .- Reviewing:
- McNeill KM et al., Emerg Infect Dis 1999 Nov/Dec; 5:
798 801 .
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DAY-CARE-CENTER INFECTIONS DUE TO ADENOVIRUS.
- December 11, 1987
- JLB
- General Medicine
Adenoviruses are an important cause of febrile respiratory illnesses in young children. With the large number of children attending day-care centers, the epidemiology of adenovirus . . .- Reviewing:
- Pacini D L; Collier A M; Henderson F W., J Infect Dis 1987 Dec; 156:
920 927 .
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Vaccine Against Human H5N1 Virus Efficacious in Mice
- February 24, 2006
- Mary E. Wilson, MD
- Infectious Diseases
A recombinant adenovirus-vector–based vaccine with the H5 gene protected mice against lethal H5N1 challenge.- Reviewing:
- Hoelscher MA et al., Lancet 2006 Feb 11; 367:475-81.
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A Single Shot for Nicotine Addiction
- July 23, 2012
- Barbara Geller, MD
- Psychiatry
In animals, a vaccine using an adeno-associated viral vector that expresses high levels of an antinicotine antibody shows persistent effects.- Reviewing:
- Hicks MJ et al., Sci Transl Med 2012 Jun 27;:
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Phase 1 Clinical Trials of Two HIV-1 Vaccine Candidates
- December 22, 2006
- Dan H. Barouch, MD, PhD
- HIV/AIDS
Two studies clearly demonstrate the safety and immunogenicity of a plasmid DNA vaccine and an rAd5 vector-based vaccine expressing a multivalent set of HIV-1 antigens.- Reviewing:
- Graham BS et al., J Infect Dis 2006 Dec 15; 194:1650-60. Catanzaro AT et al., J Infect Dis 2006 Dec 15; 194:1638-49. Robinson HL and Weinhold KJ., J Infect Dis 2006 Dec 15; 194:1625-7.
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ANOTHER SUCCESS WITH VIRAL GENE THERAPY FOR CANCER IN A MOUSE.
- November 8, 1996
- AL Komaroff
- General Medicine
Mutations of the tumor suppressor gene called p53 are perhaps the most important known genetic abnormalities in human cancer. One group recently reported using a . . .- Reviewing:
- Bischoff JR et al., Science 1996 Oct 18; 274:
373 376 .
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