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Search for Kawasaki disease in all Journal Watch editions
Physician-authored summaries on the latest research on Kawasaki disease, editorials on Kawasaki disease, and perspectives on Kawasaki disease - drawn from the top medical journals.
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You searched for: Kawasaki disease
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Adding Prednisolone to Standard Immunoglobulin Treatment Is Beneficial in High-Risk Kawasaki Disease Free
The beneficial effects of adding prednisolone are impressive in this randomized study.- Reviewing:
- Kobayashi T et al., Lancet 2012 Mar 8;: Son MBF and Newburger JW., Lancet 2012 Mar 8;:
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FCGR2A as a Susceptibility Locus for Kawasaki Disease
- January 20, 2012
- Kenneth Y. Tsai, MD, PhD
- Dermatology
A genome-wide association study points to a susceptibility locus linking Kawasaki disease to an immune mediator.- Reviewing:
- Khor CC et al., Nat Genet 2011 Nov 13; 43:1241.
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Combination Corticosteroid plus IVIG for Treatment-Resistant Kawasaki Disease
- January 13, 2012
- Mary Wu Chang, MD
- Dermatology
Adding methylprednisolone to IV immunoglobulin eliminated fever and led to greater coronary artery dimension in children predicted to be IVIG-resistant.- Reviewing:
- Ogata S et al., Pediatrics 2011 Dec 5;:
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Adults with a Pediatric Disease Free
- May 28, 2010
- Jan V. Hirschmann, MD
- Dermatology
Consider Kawasaki disease in adults with protracted fever and a diffuse rash.- Reviewing:
- Gomard-Mennesson E et al., Medicine (Baltimore) 2010 May; 89:149.
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Kawasaki Disease Outside the Usual Age Range
- September 23, 2009
- Robert S. Baltimore, MD
- Infectious Diseases
KD in children younger than 1 year or older than 9 years was associated with an increase in coronary artery abnormalities.- Reviewing:
- Manlhiot C et al., Pediatrics 2009 Sep; 124:e410.
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Kawasaki Disease: Predicting Treatment Nonresponse
- October 1, 2008
- Robert S. Baltimore, MD
- Infectious Diseases
Low albumin levels, high band counts, and abnormal initial echocardiography results were associated with poor response to IVIG treatment.- Reviewing:
- Ashouri N et al., J Pediatr 2008 Sep; 153:365.
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Kawasaki Disease: Update on Genetic Susceptibility Free
- January 25, 2008
- Mary Wu Chang, MD
- Dermatology
Researchers identify a SNP associated with susceptibility to KD and eventual development of coronary disease in affected patients.- Reviewing:
- Onouchi Y et al., Nat Genet 2008 Jan; 40:35.
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Do Corticosteroids Improve Outcome in Kawasaki Disease? Free
- February 14, 2007
- Mary Wu Chang, MD
- Dermatology
Intravenous methylprednisolone is not indicated for the primary treatment of acute KD in children.- Reviewing:
- Newburger JW et al., N Engl J Med 2007 Feb 15; 356:663-75. Burns JC., N Engl J Med 2007 Feb 15; 356:659-61.
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Treatment of Kawasaki Disease Free
- February 14, 2007
- Howard Bauchner, MD
- Pediatrics and Adolescent Medicine
These data do not support adding IV steroids to routine treatment.- Reviewing:
- Newburger JW et al., N Engl J Med 2007 Feb 15; 356:663-75. Burns JC., N Engl J Med 2007 Feb 15; 356:659-61.
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Steroids for Children with Kawasaki Disease?
- February 14, 2007
- Robert S. Baltimore, MD
- Infectious Diseases
Giving children with Kawasaki disease a pulse of methylprednisolone did not improve treatment outcome.- Reviewing:
- Newburger JW et al., N Engl J Med 2007 Feb 15; 356:663-75.
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Adding Steroids Improves Outcomes in Children with Kawasaki Disease
- November 15, 2006
- Cornelius W. Van Niel, MD
- Pediatrics and Adolescent Medicine
Intravenous immunoglobulin plus steroids improved outcomes in Japanese children with Kawasaki disease.- Reviewing:
- Inoue Y et al., J Pediatr 2006 Sep; 149:336-41. Burns JC., J Pediatr 2006 Sep; 149:291-2.
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Steroids in Primary Therapy for Kawasaki Disease
- November 8, 2006
- Robert S. Baltimore, MD
- Infectious Diseases
A multicenter study conducted in Japan showed short-term improvement in inflammation, but long-term cardiac results remain unclear.- Reviewing:
- Inoue Y et al., J Pediatr 2006 Sep; 149:336-41. Burns JC., J Pediatr 2006 Sep; 149:291-2.
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IVIG in Kawasaki Disease: Different Brands, Different Results
- February 14, 2006
- Mary Wu Chang, MD
- Dermatology
The standard treatment for Kawasaki disease (KD) in children is intravenous immunoglobulin (IVIG) and aspirin. Although this treatment protocol is standardized, the production of IVIG . . .- Reviewing:
- Tsai MH et al., J Pediatr 2006 Jan; 148:38-43. Stiehm ER., J Pediatr 2006 Jan; 148:6-8.
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Treating Kawasaki Disease: Brand of IVIG Matters
- February 7, 2006
- Robert S. Baltimore, MD
- Infectious Diseases
One brand, prepared with β-propiolactone, was associated with significantly higher rates of nonresponsiveness and of coronary artery abnormalities at convalescence.- Reviewing:
- Tsai MH et al., J Pediatr 2006 Jan; 148:38-43.
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Corticosteroids for Kawasaki Disease?
- October 25, 2005
- Howard Bauchner, MD
- General Medicine
Intravenous immune globulin (IVIG) is effective for prevention of coronary artery aneurysms in Kawasaki disease (KD). However, about 10% of children with KD still develop . . .- Reviewing:
- Wooditch AC and Aronoff SC., Pediatrics 2005 Oct; 116:989-95.
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Kawasaki Disease: New Information About Diagnosis, Management, and Treatment
- January 14, 2005
- Howard Bauchner, MD
- Pediatrics and Adolescent Medicine
The American Heart Association recently released a scientific statement, endorsed by the American Academy of Pediatrics, regarding Kawasaki disease (KD). Approximately 4000 children are hospitalized . . .- Reviewing:
- Newburger JW et al., Circulation 2004 Oct 26; 110:2747-71.
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Kawasaki Disease: Evidence of Benefit with Corticosteroids
- August 25, 2003
- Robert S. Baltimore, MD
- Infectious Diseases
Kawasaki disease is an acute systemic vasculitis that presumably is infectious, although no infectious cause has been discovered. The major complication is the development of . . .- Reviewing:
- Sundel RP et al., J Pediatr 2003 Jun; 142:611-6.
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Early Treatment of Kawasaki Disease May Be Beneficial
- June 7, 2002
- Robert S. Baltimore, MD
- Infectious Diseases
Kawasaki disease (KD) is a childhood vasculitis of unknown etiology, probably caused by a microorganism. Its major disabling outcomes, coronary-artery ectasias and aneurysms, can mostly . . .- Reviewing:
- Tse SM et al., J Pediatr 2002 Apr; 140:450-5.
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Whither Adolescents with Kawasaki Disease?
- April 1, 2002
- Elizabeth R. McAnarney, MD
- Pediatrics and Adolescent Medicine
Although physicians are becoming more familiar with the clinical presentation and sequelae of Kawasaki disease (KD), its etiology remains uncertain. Researchers in Japan linked data . . .- Reviewing:
- Hirata S et al., Arch Pediatr Adolesc Med 2002 Jan; 156:77-80.
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Is Kawasaki Disease Associated with Chlamydia pneumoniae?
- August 24, 2000
- LM Mundy
- Infectious Diseases
Kawasaki disease (KD) is an acute, febrile, multisystem vasculitis that can cause coronary artery disease. The causative agent of KD remains unknown, although it is . . .- Reviewing:
- Strigl S et al., J Infect Dis 2000 Jun; 181:
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