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Search for HDL cholesterol in all Journal Watch editions
Physician-authored summaries on the latest research on HDL cholesterol, editorials on HDL cholesterol, and perspectives on HDL cholesterol - drawn from the top medical journals.
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You searched for: HDL cholesterol
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HDL Cholesterol: Causal or Just a Marker for Coronary Risk?
- June 5, 2012
- Bruce Soloway, MD
- General Medicine
Genetically elevated HDL cholesterol level was not associated with lower risk for myocardial infarction.- Reviewing:
- Voight BF et al., Lancet 2012 May 17;: Harrison SC et al., Lancet 2012 May 17;:
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What's the Predictive Value of Cholesterol Fractions Other Than LDL?
- April 3, 2012
- Thomas L. Schwenk, MD
- General Medicine
In patients treated with statins, non–HDL cholesterol was the best predictor of CVD risk.- Reviewing:
- Boekholdt SM et al., JAMA 2012 Mar 28; 307:1302.
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Niacin Is Ineffective in Patients with Established Cardiovascular Disease Free
- November 15, 2011
- Allan S. Brett, MD
- General Medicine
Niacin plus simvastatin was no better than simvastatin alone.
CME Exam- Reviewing:
- The AIM-HIGH Investigators., N Engl J Med 2011 Nov 15;:
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In Healthy Statin Recipients, Low HDL Might Not Confer Risk After All
- August 12, 2010
- Bruce Soloway, MD
- General Medicine
HDL cholesterol level was not associated with cardiovascular risk in the JUPITER trial's rosuvastatin group.- Reviewing:
- Ridker PM et al., Lancet 2010 Jul 31; 376:333.
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HDL and Cardiovascular Risk in the Presence of Very Low LDL
- August 4, 2010
- Beat J. Meyer, MD
- Cardiology
HDL levels were not associated with residual cardiovascular risk in patients treated with potent statin therapy.
CME Exam- Reviewing:
- Ridker PM et al. for the JUPITER Trial Study Group., Lancet 2010 Jul 31; 376:333. Hausenloy DJ et al., Lancet 2010 Jul 31; 376:305.
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Does HDL Matter When Statins Are Working? Free
- September 26, 2007
- Harlan M. Krumholz, MD, SM
- Cardiology
In a post hoc analysis of TNT trial data, HDL levels predicted cardiovascular events in patients with very low LDL levels.- Reviewing:
- Barter P et al. for the Treating to New Targets Investigators., N Engl J Med 2007 Sep 27; 357:1301.
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HDL Levels and Cardiovascular Risk in Patients with Very Low LDL Levels Free
- September 26, 2007
- Allan S. Brett, MD
- General Medicine
HDL level was inversely correlated with cardiovascular events, regardless of LDL level.- Reviewing:
- Barter P et al., N Engl J Med 2007 Sep 27; 357:1301.
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Fibrates Improved Cholesterol Levels in Patients with Chronic Kidney Disease
- November 6, 2012
- Kirsten E. Fleischmann, MD, MPH
- General Medicine
But rising serum creatinine levels and decreasing glomerular filtration rate also were noted in a meta-analysis.- Reviewing:
- Jun M et al., J Am Coll Cardiol 2012 Nov 13; 60:2061. McCullough PA and Di Loreto MJ., J Am Coll Cardiol 2012 Nov 13; 60:2072.
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Fewer Americans Have High Cholesterol Free
- April 26, 2012
- Physician's First Watch
The percentage of American adults with high cholesterol declined by 27% from 1999 to 2010, according to new NHANES data reported by the CDC. In... -
Non-HDL Cholesterol Seems a Better Target Than LDL to Gauge Statin Therapy Free
- March 28, 2012
- Physician's First Watch
LDL cholesterol levels may not be the best target for statin therapy, according to a JAMA meta-analysis.Researchers examined patient data from eight randomized... -
Supplementation with Niacin or ω-3 Fatty Acids Is Ineffective for Secondary Prevention
- December 29, 2011
- Jamaluddin Moloo, MD, MPH
- General Medicine
Neither supplement prevented adverse cardiovascular events. -
Rosuvastatin and Atorvastatin Equally Effective at Reducing Atheroma Volume Free
- November 15, 2011
- JoAnne M. Foody, MD
- Cardiology
High doses of the drugs resulted in similar degrees of atherosclerosis regression, despite greater reductions in LDL levels with rosuvastatin.
CME Exam- Reviewing:
- Nicholls SJ et al., N Engl J Med 2011 Nov 15;:
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Evacetrapib Raises HDL and Lowers LDL — but Then What?
- November 15, 2011
- JoAnne M. Foody, MD
- Cardiology
The cholesterol ester transfer protein inhibitor evacetrapib had very favorable lipid effects, but the trial was small and lasted only 12 weeks.- Reviewing:
- Nicholls SJ et al., JAMA 2011 Nov 16; 306:2099. Cannon CP., JAMA 2011 Nov 16; 306:2153.
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Serum Cholesterol Might Not Affect Mortality in Elders
- November 8, 2011
- Allan S. Brett, MD
- General Medicine
In healthy older persons, high cholesterol levels were associated with lower noncardiovascular-related mortality.- Reviewing:
- Newson RS et al., J Am Geriatr Soc 2011 Oct; 59:1779.
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Inhibition of microRNA Raises HDL Cholesterol and Lowers Triglycerides in Monkeys
- November 3, 2011
- Anthony L. Komaroff, MD
- General Medicine
Two microRNAs might be key conductors of an orchestrated multigene response that affects HDL cholesterol and triglyceride levels.- Reviewing:
- Rayner KJ et al., Nature 2011 Oct 20; 478:404.
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Xanthelasma, but Not Arcus Senilis, Predicts Atherosclerotic Vascular Disease and Death
- October 21, 2011
- Jeffrey P. Callen, MD
- Dermatology
A relatively common clinical finding is a marker of increased risk for cardiovascular disease.- Reviewing:
- Christoffersen M et al., BMJ 2011 Sep 15; 343:d5497.
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Switching Antipsychotics May Reduce Metabolic Problems
- August 22, 2011
- Joel Yager, MD
- Psychiatry
Even so, monitoring for new adverse effects and the possible loss of antipsychotic effectiveness is critical.- Reviewing:
- Stroup TS et al., Am J Psychiatry 2011 Jul 18;:
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High-Selenium Yeast Supplementation Doesn't Lower Plasma Lipid Levels
- June 16, 2011
- Jamaluddin Moloo, MD, MPH
- General Medicine
Selenium supplementation should not be recommended.
CME Exam- Reviewing:
- Rayman MP et al., Ann Intern Med 2011 May 17; 154:656.
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AIM-HIGH Halted: A Death Knell for the HDL Hypothesis? Six Experts Weigh In Free
- June 8, 2011
- Cardiology
Raising HDL levels with niacin failed to affect clinical outcomes. -
Five Lessons from Niaspan's Disappointing Study Free
- June 7, 2011
- Harlan M. Krumholz, MD, SM
- General Medicine
Adapted from a post on Dr. Harlan Krumholz's Outcomes blog at Forbes.com
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