Featured Article
SUMMARY AND COMMENT
Killing in Combat and Suicidal IdeationFree
- May 21, 2012
- Deborah Cowley, MD
- Psychiatry
Veterans who had higher rates of killing in combat are at elevated risk for suicidal thoughts.
- Reviewing:
- Maguen S et al. Depress Anxiety 2012 Apr 13
Recent Articles
SUMMARY AND COMMENT
Continuous Infusion vs. Intermittent Bolus Dosing of Diuretics in Patients with Heart Failure
- May 21, 2012
- Dustin T. Smith, MD, and Daniel D. Dressler, MD, MSc, SFHM
- Hospital Medicine
A meta-analysis supports continuous infusion of furosemide but does not answer important questions regarding clinical outcomes.
- Reviewing:
- Amer M et al. J Hosp Med 2012 Mar; 7:270
SUMMARY AND COMMENT
Efavirenz Better than Nevirapine for Most PatientsFree
- May 21, 2012
- Charles B. Hicks, MD
- HIV/AIDS Clinical Care
Efavirenz was associated with better outcomes than nevirapine in a large, well-designed cohort analysis of >20,000 patients initiating ART.
- Reviewing:
- The HIV-CAUSAL Collaboration. AIDS 2012 Apr 26
SUMMARY AND COMMENT
Once-Daily Darunavir and the Brain
- May 21, 2012
- Wajid Siddiqui, MD, and Helmut Albrecht, MD
- HIV/AIDS Clinical Care
Once-daily dosing of darunavir is associated with lower drug concentrations in the cerebrospinal fluid than twice-daily dosing, but the clinical relevance of this observation remains unclear.
- Reviewing:
- Calcagno A et al. AIDS 2012 May 3
SUMMARY AND COMMENT
Effects of Contemporary ART Regimens on Inflammatory Markers
- May 21, 2012
- Keith Henry, MD
- HIV/AIDS Clinical Care
Certain markers decreased after ART initiation, regardless of regimen, whereas changes in other markers varied by regimen.
- Reviewing:
- McComsey GA et al. AIDS 2012 Apr 26
FEATURE
News on HIV and HCV Testing, and in Praise of Accurate Screening TestsFree
- May 21, 2012
- HIV/AIDS Clinical Care
Dr. Paul Sax puts the latest news in context in his blog HIV and ID Observations.
SUMMARY AND COMMENT
How Common Are Psychiatric Disorders in Adolescents? How Serious?
- May 21, 2012
- Steven Dubovsky, MD
- Psychiatry
Disease prevalence seemed high, but severity was low, in this analysis of a large population-based survey.
- Reviewing:
- Kessler RC et al. Arch Gen Psychiatry 2012 Apr; 69:372
SUMMARY AND COMMENT
A Link Between Epilepsy and Psychosis
- May 21, 2012
- Steven Dubovsky, MD
- Psychiatry
Epilepsy and psychotic illness co-occur at elevated rates within individuals and within families.
- Reviewing:
- Clarke MC et al. Biol Psychiatry 2012 May 1; 71:836
SUMMARY AND COMMENT
Interaction Between SSRIs and NSAIDs? Now It's Missing
- May 21, 2012
- Jonathan Silver, MD
- Psychiatry
Unlike a previous study, this one shows that NSAID use does not affect antidepressant response.
- Reviewing:
- Uher R et al. Psychol Med 2012 Mar 6
SUMMARY AND COMMENT
A New Model for the Brain System in Major Depression
- May 21, 2012
- Joel Yager, MD
- Psychiatry
In patients with major depression, negative information enhances limbic area responses but fails to adequately engage the dorsolateral prefrontal cortex for contextual processing and reappraisal.
- Reviewing:
- Hamilton JP et al. Am J Psychiatry 2012 Apr 25
SUMMARY AND COMMENT
Rats Behaving Badly: Biological, Transgenerational Transmission of Intimate Partner Violence
- May 21, 2012
- Joel Yager, MD
- Psychiatry
Even in the absence of social learning, male rats with violent fathers show aggression toward their female partners.
- Reviewing:
- Cordero MI et al. Transl Psychiatry 2012 Apr 24



