From the publishers of The New England Journal of Medicine

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SUMMARY AND COMMENT

Long-Term Benefits and Risks of Methotrexate in Crohn DiseaseFree

In patients previously treated with thiopurine, risk for adverse reaction was low with methotrexate monotherapy, but so was the rate of sustained response.

Recent Articles

SUMMARY AND COMMENT

Music Therapy in the ICU — Another Way to Lower Sedation Use?Free

Awake intensive care unit patients who received music therapy were less anxious than those who did not.

SUMMARY AND COMMENT

Metformin vs. Glipizide for Patients with Diabetes and Coronary Disease

Metformin was associated with better cardiovascular outcomes.

SUMMARY AND COMMENT

Targeting High-Dose Statins in Patients with Stable Angina

A rule based on 13 clinical factors identified patients at low or high risk for adverse vascular events.

SUMMARY AND COMMENT

Gene Therapy Protects Rodents from Severe Pandemic Human Influenza

A novel vaccine might protect against many pandemic strains.

CORRECTION

Correction: Tamoxifen and Raloxifene to Prevent Primary Breast CancerFree

A correction to a summary published on June 13, 2013

MEETING REPORT

ASCO 2013 Report — Breast CancerFree

A review of the latest treatment regimens

MEETING REPORT

ASCO 2013 Report: Genitourinary CancerFree

Highlights of the latest research in renal, germ cell, and prostate cancers

SUMMARY AND COMMENT

Adjuvant Radiotherapy in Older Women with Early Breast Cancer: Benefits QuestionedFree

Adding irradiation to tamoxifen after lumpectomy was associated with modestly lower risk for local-regional recurrence but no survival advantage.

SUMMARY AND COMMENT

Blood Transfusions Alloimmunize Patients with Sickle Cell DiseaseFree

Alloimmunization occurs in black patients despite transfusing phenotype-matched red blood cells from black donors.

SUMMARY AND COMMENT

Earlier Mortality with Restless Legs SyndromeFree

Results from a Health Professionals Follow-up Study analysis support an association.

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