From the publishers of The New England Journal of Medicine

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Featured Article

Psychiatry Supporting Image

SUMMARY AND COMMENT

Diabetes, Depression, and Disease Control

In patients with diabetes, depression is associated with reduced compliance with medical treatments and worse disease control.

Recent Articles

SUMMARY AND COMMENT

Oral Alternative to Warfarin for Venous Thromboembolism?

Dabigatran was safe and effective and had advantages over warfarin.

SUMMARY AND COMMENT

Immediate vs. Deferred Treatment in Prostate Cancer

Deferral with watchful waiting appears to be safe in older men with low-risk cancer.

SUMMARY AND COMMENT

Chronic Musculoskeletal Pain Contributes to Risk for Falls

Risk was associated with three pain measures — number of sites, severity, and functional impairment.

SUMMARY AND COMMENT

HPV-Associated Head and Neck Cancers

A report highlights recent discoveries about this clinical subtype of head and neck cancer.

SUMMARY AND COMMENT

A Promising Regimen for Extranodal NK/T-Cell Lymphoma?

Patients who received concurrent chemoradiotherapy followed by combination chemotherapy achieved high response rates and durable remissions.

SUMMARY AND COMMENT

Satraplatin in Advanced Prostate Cancer

Satraplatin was better than placebo in terms of progression-free survival but not overall survival.

SUMMARY AND COMMENT

Dabigatran versus Warfarin in Patients with Atrial Fibrillation

  • Neurology

A large trial suggests dabigatran's noninferiority to warfarin in preventing strokes, but many questions remain to be answered.

SUMMARY AND COMMENT

Chest X-Rays Are Overused in the ICU

Routine daily chest x-rays are unnecessary in most intubated and mechanically ventilated patients.

CLINICAL PRACTICE GUIDELINE WATCH

Updated DHHS Guidelines on HIV TreatmentFree

The new guidelines recommend that lifelong ART be provided to asymptomatic HIV-infected patients with CD4 counts ≤500 cells/mm3. They also detail the specific components of "preferred" regimens.

CLINICAL PRACTICE GUIDELINE WATCH

WHO Updates HIV Treatment RecommendationsFree

New WHO recommendations endorse earlier ART initiation for HIV-infected adolescents and adults and an even more-aggressive approach for those coinfected with TB or HBV.

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