Featured Article
ANTIRETROVIRAL ROUNDS
Is She or Isn't She?Free
- February 8, 2010
- HIV/AIDS Clinical Care
An HIV-infected pregnant woman says she's taking her antiretrovirals — but the blood test results say otherwise. How would you manage?
Special Notice
News from the 2009 San Antonio Breast Cancer Symposium
The Editor-in-Chief of Journal Watch Oncology and Hematology discusses key findings presented at the 2009 San Antonio Breast Cancer Symposium.
Recent Articles
CLINICAL PRACTICE GUIDELINE WATCH
Recommended Adult Immunization Schedule for 2010
- February 9, 2010
- Richard Saitz, MD, MPH, FACP, FASAM
- General Medicine
Few changes this year
- Reviewing:
- Advisory Committee on Immunization Practices. Ann Intern Med 2010 Jan 5; 152:36
SUMMARY AND COMMENT
Risk Index Is Adequate for Predicting Perioperative Cardiac Complications
- February 9, 2010
- Richard Saitz, MD, MPH, FACP, FASAM
- General Medicine
But the RCRI is not so predictive for death or for complications of vascular surgery.
- Reviewing:
- Ford MK et al. Ann Intern Med 2010 Jan 5; 152:26
SUMMARY AND COMMENT
Cultural Competence Training Isn't Associated with Better Diabetes Outcomes
- February 9, 2010
- Richard Saitz, MD, MPH, FACP, FASAM
- General Medicine
Awareness of racial disparities didn't translate into better glucose, lipid, or blood pressure control.
- Reviewing:
- Sequist TD et al. Ann Intern Med 2010 Jan 5; 152:40
SUMMARY AND COMMENT
Pregnancy and Childbirth in Women with MSFree
- February 9, 2010
- Maria K. Houtchens, MD, MMSci
- Neurology
Two studies add important information about the mutual influences of pregnancy and MS.
- Reviewing:
- D'hooghe MB et al. J Neurol Neurosurg Psychiatry 2010 Jan; 81:38
SUMMARY AND COMMENT
Delayed Cerebral Thrombosis After Pneumococcal Meningitis
- February 9, 2010
- Joseph R. Zunt, MD, MPH
- Neurology
A case-series analysis suggests that delayed stroke after initial good recovery may be an immune-mediated phenomenon in patients treated with adjunctive dexamethasone therapy.
- Reviewing:
- Schut ES et al. Neurology 2009 Dec 8; 73:1988
SUMMARY AND COMMENT
Diffusion-Weighted Imaging in Normal-Pressure Hydrocephalus
- February 9, 2010
- Joshua P. Klein, MD, PhD
- Neurology
Can DWI differentiate reversible changes caused by NPH from irreversible microangiopathic changes within periventricular white matter?
- Reviewing:
- Tullberg M et al. Acta Neurol Scand 2009 Oct; 120:226
SUMMARY AND COMMENT
High-Flow Oxygen for Cluster Headache
- February 9, 2010
- Mark W. Green, MD
- Neurology
A randomized crossover trial finds this treatment effective.
- Reviewing:
- Cohen AS et al. JAMA 2009 Dec 9; 302:2451
SUMMARY AND COMMENT
Imatinib Dosing for Patients with Chronic-Phase CML
- February 9, 2010
- Michael E. Williams, MD
- Oncology and Hematology
Higher dosing was associated with more early-onset responses than standard dosing, but response rates at each dose were similar after 1 year of therapy.
- Reviewing:
- Cortes JE et al. J Clin Oncol 2010 Jan 20; 28:424
SUMMARY AND COMMENT
Nilotinib as Initial Therapy for Patients with CML
- February 9, 2010
- Michael E. Williams, MD
- Oncology and Hematology
In two studies, treatment with nilotinib resulted in rapid induction and high rates of remission in patients with chronic-phase CML.
- Reviewing:
- Cortes JE et al. J Clin Oncol 2010 Jan 20; 28:392
SUMMARY AND COMMENT
Initial Antiretroviral Therapy — Switching Still Common
- February 8, 2010
- Paul E. Sax, MD
- HIV/AIDS Clinical Care
In an observational cohort study, treatment changes within the first year of therapy were common but did not reduce rates of virologic suppression.
- Reviewing:
- Elzi L et al. Arch Intern Med 2010 Jan 11; 170:57